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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Parenthetical) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017
Cost of product revenue |  |  |  |
Stock-based compensation | $ 2 | $ 19 | $ 5 | $ 33
Research and development |  |  |  |
Stock-based compensation | 3,286 | 3,067 | 6,478 | 6,079
Sales, general and administrative |  |  |  |
Stock-based compensation | $ (1,400) | $ 3,523 | $ 2,919 | $ 7,093

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