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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Revenue        
Revenue $ 81,282 $ 56,915 $ 236,523 $ 184,409
Cost of revenue        
Cost of product revenue 13,157 9,661 35,989 30,281
Cost of contract and other revenue 1,456 1,267 4,029 4,000
Amortization of acquired intangible assets 3,813 4,336 12,638 13,016
Cost of revenue 18,426 15,264 52,656 47,297
Gross profit 62,856 41,651 183,867 137,112
Operating expenses:        
Research and development 35,592 33,733 99,415 105,085
Sales, general and administrative 22,210 20,182 67,956 65,209
Amortization of acquired intangible assets 359 236 817 832
Restructuring charges 0 0 368 836
Change in fair value of earn-out liability 0 0 0 (1,800)
Total operating expenses 58,161 54,151 168,556 170,162
Operating income (loss) 4,695 (12,500) 15,311 (33,050)
Interest income and other income (expense), net 2,726 3,554 8,088 14,685
Interest expense (2,672) (2,586) (7,969) (7,721)
Interest and other income (expense), net 54 968 119 6,964
Income (loss) before income taxes 4,749 (11,532) 15,430 (26,086)
Provision for income taxes 1,073 1,205 3,201 2,330
Net income (loss) $ 3,676 $ (12,737) $ 12,229 $ (28,416)
Net income (loss) per share:        
Earnings per share, basic $ 0.03 $ (0.11) $ 0.11 $ (0.25)
Earnings per share, diluted $ 0.03 $ (0.11) $ 0.11 $ (0.25)
Weighted-average shares used in per share calculation:        
Basic (in shares) 108,989 113,828 111,103 113,437
Diluted (in shares) 113,661 113,828 114,954 113,437
Product revenue        
Revenue        
Revenue $ 36,710 $ 29,769 $ 98,661 $ 92,222
Royalties        
Revenue        
Revenue 33,044 16,602 103,813 56,828
Contract and other revenue        
Revenue        
Revenue $ 11,528 $ 10,544 $ 34,049 $ 35,359