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Collaboration Agreements (Ipsen Collaboration) (Details) | 3 Months Ended |  |
--- | --- | --- | ---
Mar. 31, 2017 USD ($) | Dec. 31, 2016 USD ($) milestone | Nov. 29, 2016 USD ($) | Feb. 28, 2016 USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Current portion of deferred revenue | $ 30,662,000 | $ 19,665,000 | [1] |  |
Long-term portion of deferred revenue | $ 261,236,000 | 237,094,000 | [1] |  |
GlaxoSmithKline [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Percent of royalty on net sale | 3.00% |  |  |  |
Collaborative Arrangement with Ipsen [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Upfront payment |  |  |  |  | $ 200,000,000
Non-substantive milestone payment |  |  |  | $ 60,000,000 |
Research and development arrangement performed for others, reimbursement for costs incurred, percent | 35.00% |  |  |  |
Reimbursements of certain clinical programs paid | $ 1,100,000 |  |  |  |
Current portion of deferred revenue | 19,000,000 |  |  |  |
Long-term portion of deferred revenue | 224,400,000 |  |  |  |
Collaborative Arrangement with Ipsen [Member] | Restatement Adjustment [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Deferred revenue reclassified | $ 9,000,000 |  |  |  |
Collaborative Arrangement with Ipsen [Member] | Initial [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Percent of royalty on net sale | 2.00% |  |  |  |
Royalty tier | $ 50,000,000 |  |  |  |
Collaborative Arrangement with Ipsen [Member] | Second [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Percent of royalty on net sale | 12.00% |  |  |  |
Royalty tier | $ 100,000,000 |  |  |  |
Collaborative Arrangement with Ipsen [Member] | Initial and Second [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Royalty tier | $ 150,000,000 |  |  |  |
Collaborative Arrangement with Ipsen [Member] | Initial and Second [Member] | Minimum [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Percent of royalty on net sale | 22.00% |  |  |  |
Collaborative Arrangement with Ipsen [Member] | Initial and Second [Member] | Maximum [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Percent of royalty on net sale | 26.00% |  |  |  |
Collaborative Arrangement with Ipsen [Member] | Canada [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Upfront payment |  | $ 10,000,000 |  |  |
Collaborative Arrangement with Ipsen, First Commercial Sales of Product [Member] | CABOMETYX [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Number of milestones achieved | milestone |  | 2 |  |  |
Collaborative Arrangement with Ipsen, First Commercial Sales of Product [Member] | Germany [Member] | CABOMETYX [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Revenue recognized, milestones |  | $ 10,000,000 |  |  |
[1] | The condensed consolidated balance sheet as of December 31, 2016 has been derived from the audited financial statements as of that date.

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