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Debt (Deerfield Notes) (Details) - Secured Notes [Member] - Deerfield Notes [Member] - USD ($) | 3 Months Ended |
--- | --- | ---
Mar. 31, 2017 | Dec. 31, 2016
Debt Instrument [Line Items] |  |
Aggregate principal amount | $ 113,900,000 | $ 109,800,000
Convertible debt | $ 113,349,000 | 109,122,000
Interest rate after extension option election (as a percent) | 15.00% |
Prepayment price (as a percent) | 105.00% |
Balance of unamortized closing fees and expenses | $ 400,000 | $ 400,000
Effective interest rate (as a percent) | 15.20% |
Percentage of revenues payable under collaborative arrangements (as a percent) | 15.00% |
Maximum prepayment amount under collaborative arrangements | $ 27,500,000.0 |
Mandatory prepayments | $ 8,200,000 |
Coupon Interest [Member] |  |
Debt Instrument [Line Items] |  |
Interest rate after extension option election (as a percent) | 7.50% |
Payment-in-Kind Interest [Member] |  |
Debt Instrument [Line Items] |  |
Interest rate after extension option election (as a percent) | 7.50% |

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- Definition Including the current and noncurrent portions, carrying amount of debt identified as being convertible into another form of financial instrument (typically the entity's common stock) as of the balance sheet date, which originally required full repayment more than twelve months after issuance or greater than the normal operating cycle of the company. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 210 -Section S99 -Paragraph 1 -Subparagraph (SX 210.9-03(16)) -URI http://asc.fasb.org/extlink&oid=6876686&loc=d3e534808-122878 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 210 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-03(a)(16)) -URI http://asc.fasb.org/extlink&oid=6879938&loc=d3e572229-122910 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(22)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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