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Concentrations of Credit Risk (Tables) | 6 Months Ended
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Jun. 30, 2017
Risks and Uncertainties [Abstract] |
Schedules of Concentration Risk | The following table shows the revenues earned by geographic region. Net product revenues are attributed to regions based on the delivery location. Collaboration revenues are attributed to regions based on the location of our collaboration partner's headquarters (dollars in thousands):
| Three Months Ended June 30, |  | Six Months Ended June 30,
| 2017 |  | 2016 |  | 2017 |  | 2016
U.S. | $ | 89,371 |  |  | $ | 32,192 |  |  | $ | 163,046 |  |  | $ | 45,786 |
Europe | 5,494 |  |  | 4,060 |  |  | 10,024 |  |  | 5,893 |
Japan | 4,143 |  |  | — |  |  | 6,825 |  |  | — |
The percentage of total revenues recognized by customer that represent 10% or more of total revenues was as follows:
| Three Months Ended June 30, |  | Six Months Ended June 30,
| 2017 |  | 2016 |  | 2017 |  | 2016
Diplomat Specialty Pharmacy | 23 | % |  | 52 | % |  | 24 | % |  | 53 | %
Caremark L.L.C. | 19 | % |  | 9 | % |  | 18 | % |  | 6 | %
Accredo Health, Incorporated | 14 | % |  | 7 | % |  | 13 | % |  | 5 | %
Affiliates of McKesson Corporation | 13 | % |  | 6 | % |  | 13 | % |  | 4 | %
Merck | — | % |  | — | % |  | — | % |  | 10 | %

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- Definition Tabular disclosure of the nature of a concentration, a benchmark to which it is compared, and the percentage that the risk is to the benchmark. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 275 -SubTopic 10 -Section 50 -Paragraph 18 -URI http://asc.fasb.org/extlink&oid=64851502&loc=d3e6351-108592 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 825 -SubTopic 10 -Section 50 -Paragraph 21 -URI http://asc.fasb.org/extlink&oid=73719730&loc=d3e13537-108611 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 825 -SubTopic 10 -Section 50 -Paragraph 20 -URI http://asc.fasb.org/extlink&oid=73719730&loc=d3e13531-108611 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 275 -SubTopic 10 -Section 50 -Paragraph 21 -URI http://asc.fasb.org/extlink&oid=64851502&loc=d3e6442-108592 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 275 -SubTopic 10 -Section 50 -Paragraph 16 -URI http://asc.fasb.org/extlink&oid=64851502&loc=d3e6327-108592 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 275 -SubTopic 10 -Section 50 -Paragraph 20 -URI http://asc.fasb.org/extlink&oid=64851502&loc=d3e6404-108592 + Details
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