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Property and Equipment (Tables)
6 Months Ended
Jun. 30, 2017
Property, Plant and Equipment [Abstract]  
Property and Equipment
Property and equipment consisted of the following (in thousands): 
 
June 30,
2017
 
December 31,
2016
Computer equipment and software
$
13,803

 
$
13,738

Leasehold improvements
4,715

 
6,646

Laboratory equipment
4,286

 
4,310

Furniture and fixtures
1,921

 
2,240

Construction-in-progress
16,787

 
19

 
41,512

 
26,953

Less: accumulated depreciation and amortization
(22,828
)
 
(24,882
)
Property and equipment, net
$
18,684

 
$
2,071