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Condensed Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Revenues:        
Net product revenues $ 88,004 $ 31,618 $ 156,881 $ 40,717
Collaboration revenues 11,004 4,634 23,014 10,962
Total revenues 99,008 36,252 179,895 51,679
Operating expenses:        
Cost of goods sold 3,014 1,560 6,217 2,245
Research and development 28,214 22,984 51,424 51,910
Selling, general and administrative 40,727 35,823 74,987 70,680
Restructuring (recovery) charge (60) 1,021 (32) 1,115
Total operating expenses 71,895 61,388 132,596 125,950
Income (loss) from operations 27,113 (25,136) 47,299 (74,271)
Other expense, net:        
Interest income and other, net 1,622 749 2,690 951
Interest expense (4,259) (10,451) (8,679) (20,741)
Loss on extinguishment of debt (6,239) 0 (6,239) 0
Total other expense, net (8,876) (9,702) (12,228) (19,790)
Income (loss) before income taxes 18,237 (34,838) 35,071 (94,061)
Income tax expense 581 0 715 0
Net income (loss) $ 17,656 $ (34,838) $ 34,356 $ (94,061)
Net income (loss) per share, basic (in dollars per share) $ 0.06 $ (0.15) $ 0.12 $ (0.41)
Net income (loss) per share, diluted (in dollars per share) $ 0.06 $ (0.15) $ 0.11 $ (0.41)
Shares used in computing net income (loss) per share, basic (in shares) 293,188 229,310 292,029 228,860
Shares used in computing net income (loss) per share, diluted (in shares) 311,219 229,310 310,759 228,860