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Collaboration Agreements (Ipsen Collaboration) (Details)	1 Months Ended				3 Months Ended			6 Months Ended
	Dec. 31, 2016 USD ($)		Nov. 30, 2016 USD ($)	Mar. 31, 2016 USD ($)	Jun. 30, 2017 USD ($) milestone	Dec. 31, 2016 USD ($)		Jun. 30, 2017 USD ($)	Mar. 31, 2017 USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Current portion of deferred revenue	$ 19,665,000	[1]			$ 31,255,000	$ 19,665,000	[1]	$ 31,255,000
Long-term portion of deferred revenue	237,094,000	[1]			253,663,000	237,094,000	[1]	$ 253,663,000
GlaxoSmithKline [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Percent of royalty on net sale								3.00%
Collaborative Arrangement with Ipsen [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Upfront and milestone payments				$ 200,000,000
Research and development arrangement performed for others, reimbursement for costs incurred, percent								35.00%
Reimbursements of certain clinical programs paid					2,100,000
Current portion of deferred revenue					19,000,000			$ 19,000,000
Long-term portion of deferred revenue					$ 219,700,000			$ 219,700,000
Collaborative Arrangement with Ipsen [Member] | Reclassification Adjustment [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Deferred revenue reclassified									$ 9,000,000
Collaborative Arrangement with Ipsen [Member] | Initial [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Percent of royalty on net sale								2.00%
Royalty tier								$ 50,000,000
Collaborative Arrangement with Ipsen [Member] | Second [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Percent of royalty on net sale								12.00%
Royalty tier								$ 100,000,000
Collaborative Arrangement with Ipsen [Member] | Initial and Second [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Royalty tier								$ 150,000,000
Collaborative Arrangement with Ipsen [Member] | Initial and Second [Member] | Minimum [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Percent of royalty on net sale								22.00%
Collaborative Arrangement with Ipsen [Member] | Initial and Second [Member] | Maximum [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Percent of royalty on net sale								26.00%
Collaborative Arrangement with Ipsen, Consideration for Commercialization Rights [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recognized, milestones	$ 10,000,000
Collaborative Arrangement with Ipsen, Approval of Cabozantinib by EC in Second-Line RCC [Member] | CABOMETYX [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recognized, milestones			$ 60,000,000
Collaborative Arrangement with Ipsen, First Commercial Sales of Product [Member] | CABOMETYX [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Number of milestones achieved | milestone					2
Collaborative Arrangement with Ipsen, First Commercial Sales of Product [Member] | United Kingdom [Member] | CABOMETYX [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recognized, milestones						$ 10,000,000
Collaborative Arrangement with Ipsen, First Commercial Sales of Product [Member] | Germany [Member] | CABOMETYX [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recognized, milestones					$ 10,000,000
[1] The condensed consolidated balance sheet as of December 31, 2016 has been derived from the audited financial statements as of that date.

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