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Collaboration Agreements (Tables)
3 Months Ended
Mar. 30, 2018
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Collaboration Revenues and Contract Assets and Liabilities
Collaboration revenues under the collaboration agreement with Ipsen were as follows (in thousands):
 
Three Months Ended March 31,
 
2018
 
2017
Ipsen collaboration revenues
$
53,809

 
$
4,530

Royalty revenues on ex-U.S. sales and our share of the profits and losses recognized in connection with COTELLIC’s commercialization in the U.S. were as follows (in thousands):
 
Three Months Ended March 31,
 
2018
 
2017
Royalty revenues on ex-U.S. sales
$
1,349

 
$
2,298

Profits and losses on U.S. commercialization
$
1,373

 
$
(626
)
Royalties accruing to GSK in connection with the sales of COMETRIQ and CABOMETYX are included in Cost of goods sold for net sales by us and as a reduction of Collaboration revenues for net sales by Ipsen on the accompanying Condensed Consolidated Statements of Operations. Such royalties were as follows (in thousands):
 
Three Months Ended March 31,
 
2018
 
2017
Royalties accruing to GSK
$
5,125

 
$
2,737

Collaboration revenues under the collaboration agreement with Takeda were as follows (in thousands):
 
Three Months Ended March 31,
 
2018
 
2017
Takeda collaboration revenues
$
2,917

 
$
2,682