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Condensed Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended
Mar. 30, 2018
Mar. 31, 2017
Revenues:    
Net product revenues $ 134,272 $ 68,877
Collaboration revenues 78,074 12,010
Total revenues 212,346 80,887
Operating expenses:    
Cost of goods sold 5,639 3,203
Research and development 37,757 23,210
Selling, general and administrative 52,643 34,288
Total operating expenses 96,039 60,701
Income (loss) from operations 116,307 20,186
Other income (expense), net:    
Interest income 1,895 1,113
Interest expense 0 (4,420)
Other, net 169 (45)
Total other income (expense), net 2,064 (3,352)
Income (loss) before income taxes 118,371 16,834
Income tax expense 2,514 134
Net income (loss) $ 115,857 $ 16,700
Net income per share, basic (in dollars per share) $ 0.39 $ 0.06
Net income per share, diluted (in dollars per share) $ 0.37 $ 0.05
Shares used in computing net income per share, basic (in shares) 296,421 290,870
Shares used in computing net income per share, diluted (in shares) 313,691 309,535