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Collaboration Agreements - Genentech Collaboration (Details) - Collaborative Arrangement with Genentech - COTELLIC - USD ($) $ in Thousands	3 Months Ended
	Mar. 30, 2018	Mar. 31, 2017
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Royalty revenue	$ 1,349	$ 2,298
Q4 2016
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Royalty revenue		1,100
Q1 2017
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Royalty revenue		$ 1,200

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+ References

No definition available.

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- Definition

Revenue earned during the period from the leasing or otherwise lending to a third party the entity's rights or title to certain property. Royalty revenue is derived from a percentage or stated amount of sales proceeds or revenue generated by the third party using the entity's property. Examples of property from which royalties may be derived include patents and oil and mineral rights.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.1(e))
-URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688

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