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Organization and Summary of Significant Accounting Policies - Narrative (Details) $ in Thousands | 3 Months Ended | 6 Months Ended | 23 Months Ended |  |
--- | --- | --- | --- | --- | ---
Jun. 29, 2018 USD ($) | Mar. 30, 2018 USD ($) | Jun. 30, 2017 USD ($) | Jun. 29, 2018 USD ($) segment product | Jun. 30, 2017 USD ($) | Dec. 29, 2017 USD ($) | Dec. 30, 2017 USD ($) | Feb. 29, 2016 USD ($)
Organization And Summary Of Significant Policies [Line Items] |  |  |  |  |  |  |  |  |
Number of products that entered in the commercial marketplace | product |  |  |  | 3 |  |  |  |  |
Number of business segments | segment |  |  |  | 1 |  |  |  |  |
Selling, general and administrative expense | $ 51,853 | $ 54,000 | $ 40,667 | $ 105,869 | $ 74,955 |  |  |  |
Collaboration revenues | 40,272 | 79,400 | 11,004 | 119,719 | 23,014 |  |  |  |
Total revenues | 186,108 | 213,700 | 99,008 | 399,827 | 179,895 |  |  |  |
Operating expenses | 100,338 | 97,400 | 71,895 | 197,750 | 132,596 |  |  |  |
Increase in net cash provided by investing activities |  |  |  | (91,800) | 81,719 |  |  |  |
Reduction to accumulated deficit | (1,367,316) |  |  | (1,367,316) |  | $ (1,829,172) | [1] | $ (1,570,667) |
Revenue | 31,908 |  | 9,156 | $ 100,938 | 20,370 |  |  |  |
Prompt payment discount rate |  |  |  | 2.00% |  |  |  |  |
Percent of total available discounts expected to be earned |  |  |  | 100.00% |  |  |  |  |
Products Derived from Cabozantinib |  |  |  |  |  |  |  |  |
Organization And Summary Of Significant Policies [Line Items] |  |  |  |  |  |  |  |  |
Number of products that entered in the commercial marketplace | product |  |  |  | 2 |  |  |  |  |
Collaborative Arrangement with Ipsen |  |  |  |  |  |  |  |  |
Organization And Summary Of Significant Policies [Line Items] |  |  |  |  |  |  |  |  |
Collaboration revenues | 34,043 |  | $ 5,494 | $ 87,852 | 10,024 |  |  |  |
Milestone payments earned |  |  |  |  |  | $ 125,000 |  |  |
Additional milestone achievement |  |  |  |  |  |  |  |  | $ 199,000
Collaborative Arrangement with Ipsen | HCC Filing |  |  |  |  |  |  |  |  |
Organization And Summary Of Significant Policies [Line Items] |  |  |  |  |  |  |  |  |
Milestone payments earned |  |  |  | 10,000 |  |  |  |  |
Collaborative Arrangement with Ipsen | EMA Approval - RCC |  |  |  |  |  |  |  |  |
Organization And Summary Of Significant Policies [Line Items] |  |  |  |  |  |  |  |  |
Revenue | 200 | 45,800 |  |  |  |  |  |  |
Additional milestone achievement | 50,000 |  |  | 50,000 |  |  |  |  |
Collaborative Arrangement with Ipsen | EMA Approval |  |  |  |  |  |  |  |  |
Organization And Summary Of Significant Policies [Line Items] |  |  |  |  |  |  |  |  |
Revenue |  |  |  | 46,000 |  |  |  |  |
ASU 2016-18 |  |  |  |  |  |  |  |  |
Organization And Summary Of Significant Policies [Line Items] |  |  |  |  |  |  |  |  |
Increase in net cash provided by investing activities |  |  |  |  | $ 500 |  |  |  |
ASU 2014-09 | Adjustments Due to the Adoption of Topic 606 |  |  |  |  |  |  |  |  |
Organization And Summary Of Significant Policies [Line Items] |  |  |  |  |  |  |  |  |
Collaboration revenues | (54,148) |  |  | (22,750) |  |  |  |  |
Total revenues | $ (54,148) |  |  | $ (22,750) |  |  |  |  |
Reduction to accumulated deficit |  |  |  |  |  |  |  | $ 258,505 |
Adjustment |  |  |  |  |  |  |  |  |
Organization And Summary Of Significant Policies [Line Items] |  |  |  |  |  |  |  |  |
Selling, general and administrative expense |  | 1,400 |  |  |  |  |  |  |
Collaboration revenues |  | 1,400 |  |  |  |  |  |  |
As Previously Reported |  |  |  |  |  |  |  |  |
Organization And Summary Of Significant Policies [Line Items] |  |  |  |  |  |  |  |  |
Selling, general and administrative expense |  | 52,600 |  |  |  |  |  |  |
Collaboration revenues |  | 78,100 |  |  |  |  |  |  |
Total revenues |  | 212,300 |  |  |  |  |  |  |
Operating expenses |  | $ 96,000 |  |  |  |  |  |  |
[1] | The Condensed Consolidated Balance Sheet as of December 31, 2017 has been derived from the audited financial statements as of that date.

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