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Collaboration Agreements - Collaboration Revenues under the Collaboration Agreement with Ipsen (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
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Jun. 29, 2018 | Mar. 30, 2018 | Jun. 30, 2017 | Jun. 29, 2018 | Jun. 30, 2017
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Collaboration revenues | $ 40,272 | $ 79,400 | $ 11,004 | $ 119,719 | $ 23,014
Collaborative Arrangement with Ipsen |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Collaboration revenues | $ 34,043 |  | $ 5,494 | $ 87,852 | $ 10,024

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- Definition Amount of revenue earned from products sold or services provided under the terms of a contract, including, but not limited to, government contracts and construction contracts, classified as other. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.1) -URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688 + Details
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