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Collaboration Agreements - Royalty Revenues under the Collaboration Agreement with GlaxoSmithKline (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 29, 2018
Jun. 30, 2017
Jun. 29, 2018
Jun. 30, 2017
Collaboration Agreement with GlaxoSmithKline        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Royalties accruing to GSK $ 5,628 $ 2,962 $ 10,753 $ 5,363