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Revenues - Revenues by Disaggregated Category (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 28, 2018 | Sep. 29, 2017 | Sep. 28, 2018 | Sep. 29, 2017
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | $ (225,397) | $ (152,510) | $ (625,224) | $ (332,405)
Net product revenues |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | (162,946) | (96,416) | (443,054) | (253,297)
Gross product revenues |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | (193,356) | (111,148) | (525,438) | (289,365)
Discounts and allowances |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | (30,410) | (14,732) | (82,384) | (36,068)
Total collaboration revenues |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | (62,451) | (56,094) | (182,170) | (79,108)
License revenues |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | (51,323) | (54,335) | (152,261) | (74,706)
Research and development services revenues |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | (10,560) | (2,316) | (27,464) | (5,623)
Other collaboration revenues |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | $ (568) | $ 557 | $ (2,445) | $ 1,221

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