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Organization and Summary of Significant Accounting Policies - Impact of Adoption of Topic 606 and Topic 842 on the Condensed Consolidated Balance Sheet (Details) - USD ($)
$ in Thousands
Sep. 28, 2018
Dec. 30, 2017
Dec. 29, 2017
Contract assets: unbilled collaboration revenue, gross:      
Current portion $ 24,489 $ 9,588 $ 0 [1]
Long-term portion 0 12,247  
Trade and other receivables 104,634 88,935 81,192 [1]
Property and equipment, net 51,046 11,213 25,743 [1]
Operating lease right-of-use assets 5,989 8,579 0 [1]
Contract liabilities: deferred revenue, gross:      
Current portion 0 8,393 31,984 [1]
Current portion 2,268 25,441 238,520 [1]
Other current liabilities 15,900 19,323 16,150 [1]
Long-term portion of lease liabilities 14,983 13,324  
Other long-term liabilities 2,607 1,705 2,113 [1]
Accumulated deficit $ (1,240,452) (1,570,434) (1,829,172) [1]
Calculated under Guidance in Effect before Topic 606      
Contract assets: unbilled collaboration revenue, gross:      
Current portion     0
Long-term portion     0
Trade and other receivables     81,192
Property and equipment, net     25,743
Operating lease right-of-use assets     0
Contract liabilities: deferred revenue, gross:      
Current portion     31,984
Current portion     238,520
Other current liabilities     16,150
Long-term portion of lease liabilities     14,530
Other long-term liabilities     2,113
Accumulated deficit     $ (1,829,172)
ASU 2014-09 | Difference between Revenue Guidance in Effect before and after Topic 606      
Contract assets: unbilled collaboration revenue, gross:      
Current portion   9,588  
Long-term portion   12,247  
Contract liabilities: deferred revenue, gross:      
Current portion   (23,591)  
Current portion   (213,079)  
Accumulated deficit   258,505  
Restatement Adjustment | ASU 2016-02      
Contract assets: unbilled collaboration revenue, gross:      
Trade and other receivables   7,743  
Property and equipment, net   (14,530)  
Operating lease right-of-use assets   8,579  
Contract liabilities: deferred revenue, gross:      
Other current liabilities   3,173  
Long-term portion of lease liabilities   (1,206)  
Other long-term liabilities   (408)  
Accumulated deficit   $ 233  
[1] The Condensed Consolidated Balance Sheet as of December 31, 2017 has been derived from the audited financial statements as of that date.