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Revenues - Revenues by Disaggregated Category (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 28, 2018	Sep. 29, 2017	Sep. 28, 2018	Sep. 29, 2017
Disaggregation of Revenue [Line Items]
Revenues	$ (225,397)	$ (152,510)	$ (625,224)	$ (332,405)
Net product revenues
Disaggregation of Revenue [Line Items]
Revenues	(162,946)	(96,416)	(443,054)	(253,297)
Gross product revenues
Disaggregation of Revenue [Line Items]
Revenues	(193,356)	(111,148)	(525,438)	(289,365)
Discounts and allowances
Disaggregation of Revenue [Line Items]
Revenues	(30,410)	(14,732)	(82,384)	(36,068)
Total collaboration revenues
Disaggregation of Revenue [Line Items]
Revenues	(62,451)	(56,094)	(182,170)	(79,108)
License revenues
Disaggregation of Revenue [Line Items]
Revenues	(51,323)	(54,335)	(152,261)	(74,706)
Research and development services revenues
Disaggregation of Revenue [Line Items]
Revenues	(10,560)	(2,316)	(27,464)	(5,623)
Other collaboration revenues
Disaggregation of Revenue [Line Items]
Revenues	$ (568)	$ 557	$ (2,445)	$ 1,221

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 4
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=109196051&loc=SL49130543-203045

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
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-Paragraph 1
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Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 5
-URI http://asc.fasb.org/extlink&oid=109196051&loc=SL49130545-203045

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