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Condensed Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 9 Months Ended
Sep. 28, 2018
Sep. 29, 2017
Sep. 28, 2018
Sep. 29, 2017
Revenues $ 225,397 $ 152,510 $ 625,224 $ 332,405
Operating expenses:        
Cost of goods sold 7,360 4,658 18,996 10,875
Research and development 44,741 28,543 124,986 79,967
Selling, general and administrative 48,120 38,129 153,989 113,084
Total operating expenses 100,221 71,330 297,971 203,926
Income (loss) from operations 125,176 81,180 327,253 128,479
Other income (expense), net:        
Interest income 3,507 1,133 8,099 3,497
Interest expense (1) 0 (1) (8,679)
Other, net 272 2,275 369 (3,638)
Total other income (expense), net 3,778 3,408 8,467 (8,820)
Income (loss) before income taxes 128,954 84,588 335,720 119,659
Income tax expense 2,324 3,206 5,739 3,921
Net income (loss) $ 126,630 $ 81,382 $ 329,981 $ 115,738
Net income per share, basic (in dollars per share) $ 0.42 $ 0.28 $ 1.11 $ 0.39
Net income per share, diluted (in dollars per share) $ 0.41 $ 0.26 $ 1.05 $ 0.37
Shares used in computing net income per share, basic (in shares) 298,416 294,269 297,700 292,776
Shares used in computing net income per share, diluted (in shares) 312,346 312,940 313,200 311,555
Net Product Revenues        
Revenues $ 162,946 $ 96,416 $ 443,054 $ 253,297
Collaboration Revenues        
Revenues $ 62,451 $ 56,094 $ 182,170 $ 79,108