<SEC-DOCUMENT>0000939767-18-000068.txt : 20180502
<SEC-HEADER>0000939767-18-000068.hdr.sgml : 20180502
<ACCEPTANCE-DATETIME>20180502161122
ACCESSION NUMBER:		0000939767-18-000068
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20180502
ITEM INFORMATION:		Results of Operations and Financial Condition
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20180502
DATE AS OF CHANGE:		20180502

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			EXELIXIS, INC.
		CENTRAL INDEX KEY:			0000939767
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				043257395
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0102

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-30235
		FILM NUMBER:		18799692

	BUSINESS ADDRESS:	
		STREET 1:		210 E. GRAND AVE
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
		BUSINESS PHONE:		6508377000

	MAIL ADDRESS:	
		STREET 1:		210 E. GRAND AVE
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EXELIXIS INC
		DATE OF NAME CHANGE:	20000207

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EXELIXIS PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	20000106
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>exel8-kq12018earningsrelea.htm
<DESCRIPTION>8-K
<TEXT>
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<div><a name="s60B0FE53F6BC5595AE4F8E3DE8ED5819"></a></div><div><div style="line-height:120%;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></div><div><br></div><div style="line-height:120%;padding-top:4px;text-align:center;font-size:16pt;"><font style="font-family:Calibri,sans-serif;font-size:16pt;font-weight:bold;">UNITED STATES</font></div><div style="line-height:120%;text-align:center;font-size:16pt;"><font style="font-family:Calibri,sans-serif;font-size:16pt;font-weight:bold;">SECURITIES AND EXCHANGE COMMISSION</font></div><div style="line-height:120%;text-align:center;font-size:12pt;"><font style="font-family:Calibri,sans-serif;font-size:12pt;font-weight:bold;">Washington, D.C. 20549</font><font style="font-family:Calibri,sans-serif;font-size:9pt;">&#160;</font></div><div style="line-height:120%;text-align:center;font-size:16pt;"><div style="padding-left:0px;text-indent:0px;line-height:normal;padding-top:10px;"><table cellpadding="0" cellspacing="0" style="font-family:Times New Roman;font-size:10pt;margin-left:auto;margin-right:auto;width:300px;border-collapse:collapse;text-align:left;"><tr><td colspan="1"></td></tr><tr><td style="width:300px;"></td></tr><tr><td style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;border-top:1px solid #000000;"><div style="padding-top:2px;text-align:center;font-size:16pt;"><font style="font-family:Calibri,sans-serif;font-size:16pt;font-weight:bold;">FORM 8-K</font></div></td></tr></table></div></div><div style="line-height:120%;padding-top:6px;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">CURRENT REPORT </font></div><div style="line-height:120%;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">PURSUANT TO SECTION 13 OR 15(d) OF THE </font></div><div style="line-height:120%;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">SECURITIES EXCHANGE ACT OF 1934 </font></div><div style="line-height:120%;padding-top:12px;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">Date of Report (Date of earliest event reported): </font><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">May&#160;2, 2018</font></div><div style="line-height:120%;text-align:center;font-size:16pt;"><div style="padding-left:0px;text-indent:0px;line-height:normal;padding-top:10px;"><table cellpadding="0" cellspacing="0" style="font-family:Times New Roman;font-size:10pt;margin-left:auto;margin-right:auto;width:300px;border-collapse:collapse;text-align:left;"><tr><td colspan="1"></td></tr><tr><td style="width:300px;"></td></tr><tr><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;border-top:1px solid #000000;"><div style="text-align:center;"><img src="image0a05.jpg" alt="image0a05.jpg" style="height:64px;width:190px;"></div></td></tr><tr><td style="vertical-align:top;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="padding-top:2px;text-align:center;font-size:16pt;"><font style="font-family:Calibri,sans-serif;font-size:16pt;font-weight:bold;">EXELIXIS, INC.</font></div><div style="text-align:center;font-size:8pt;"><font style="font-family:Calibri,sans-serif;font-size:8pt;">(Exact name of registrant as specified in its charter)</font></div></td></tr></table></div></div><div style="line-height:100%;text-align:center;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div><div style="line-height:120%;text-align:center;font-size:10pt;"><div style="padding-left:0px;text-indent:0px;line-height:normal;padding-top:10px;"><table cellpadding="0" cellspacing="0" style="font-family:Times New Roman;font-size:10pt;margin-left:auto;margin-right:auto;width:100%;border-collapse:collapse;text-align:left;"><tr><td colspan="3"></td></tr><tr><td style="width:34%;"></td><td style="width:33%;"></td><td style="width:33%;"></td></tr><tr><td style="vertical-align:top;padding-left:2px;padding-top:2px;padding-bottom:1px;padding-right:2px;"><div style="padding-bottom:1px;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">Delaware</font></div></td><td style="vertical-align:top;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="padding-bottom:1px;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">000-30235</font></div></td><td style="vertical-align:top;padding-left:2px;padding-top:2px;padding-bottom:1px;padding-right:2px;"><div style="padding-bottom:1px;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">04-3257395</font></div></td></tr><tr><td style="vertical-align:top;padding-left:2px;padding-top:2px;padding-bottom:1px;padding-right:2px;"><div style="padding-bottom:1px;text-align:center;text-indent:2px;font-size:8pt;"><font style="font-family:Calibri,sans-serif;font-size:8pt;">(State or Other Jurisdiction  <br>of Incorporation)</font></div></td><td style="vertical-align:top;padding-left:2px;padding-top:2px;padding-bottom:1px;padding-right:2px;"><div style="padding-bottom:1px;text-align:center;text-indent:2px;font-size:8pt;"><font style="font-family:Calibri,sans-serif;font-size:8pt;">(Commission  <br>File Number)</font></div></td><td style="vertical-align:top;padding-left:2px;padding-top:2px;padding-bottom:1px;padding-right:2px;"><div style="padding-bottom:1px;text-align:center;text-indent:2px;font-size:8pt;"><font style="font-family:Calibri,sans-serif;font-size:8pt;">(IRS Employer  <br>Identification No.)</font></div></td></tr></table></div></div><div style="line-height:120%;text-align:center;font-size:12pt;"><font style="font-family:Calibri,sans-serif;font-size:12pt;"><br></font></div><div style="line-height:120%;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">210 East Grand Ave.</font></div><div style="line-height:120%;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">South San Francisco, California 94080</font></div><div style="line-height:120%;text-align:center;font-size:8pt;"><font style="font-family:Calibri,sans-serif;font-size:8pt;">(Address of principal executive offices) (Zip Code)</font></div><div style="line-height:120%;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div style="line-height:120%;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">(650) 837-7000</font></div><div style="line-height:120%;text-align:center;font-size:8pt;"><font style="font-family:Calibri,sans-serif;font-size:8pt;">(Registrant&#8217;s telephone number, including area code) </font></div><div style="line-height:120%;text-align:center;font-size:8pt;"><font style="font-family:Calibri,sans-serif;font-size:8pt;"><br></font></div><div style="line-height:120%;padding-top:12px;text-align:left;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below): </font></div><table cellpadding="0" cellspacing="0" style="padding-top:12px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:33px;"></td><td></td></tr><tr><td style="vertical-align:top"><div style="line-height:120%;font-size:10pt;padding-left:1px;"><font style="font-family:Wingdings;font-size:10pt;">&#168;</font></div></td><td style="vertical-align:top;"><div style="line-height:120%;text-align:left;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) </font></div></td></tr></table><table cellpadding="0" cellspacing="0" style="padding-top:12px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:33px;"></td><td></td></tr><tr><td style="vertical-align:top"><div style="line-height:120%;font-size:10pt;padding-left:1px;"><font style="font-family:Wingdings;font-size:10pt;">&#168;</font></div></td><td style="vertical-align:top;"><div style="line-height:120%;text-align:left;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) </font></div></td></tr></table><table cellpadding="0" cellspacing="0" style="padding-top:12px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:33px;"></td><td></td></tr><tr><td style="vertical-align:top"><div style="line-height:120%;font-size:10pt;padding-left:1px;"><font style="font-family:Wingdings;font-size:10pt;">&#168;</font></div></td><td style="vertical-align:top;"><div style="line-height:120%;text-align:left;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) </font></div></td></tr></table><table cellpadding="0" cellspacing="0" style="padding-top:12px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:33px;"></td><td></td></tr><tr><td style="vertical-align:top"><div style="line-height:120%;font-size:10pt;padding-left:1px;"><font style="font-family:Wingdings;font-size:10pt;">&#168;</font></div></td><td style="vertical-align:top;"><div style="line-height:120%;text-align:left;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) </font></div></td></tr></table><div style="line-height:120%;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div><div style="line-height:120%;text-align:left;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (&#167;230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (&#167;240.12b-2 of this chapter). Emerging growth company</font><font style="font-family:inherit;font-size:10pt;">&#32;</font><font style="font-family:Wingdings;font-size:10pt;">&#168;</font></div><div style="line-height:120%;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div><div style="line-height:120%;text-align:justify;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.</font><font style="font-family:inherit;font-size:10pt;">&#32;</font><font style="font-family:Wingdings;font-size:10pt;">&#168;</font></div><div style="line-height:120%;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div><div><br></div><div><div style="line-height:120%;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></div><hr style="page-break-after:always"><div><a name="sFB7ED52894D959679557B6BCC7299525"></a></div><div><div style="line-height:120%;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></div><div><br></div><div style="line-height:120%;-sec-extract:summary;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">Item 2.02.  Results of Operations and Financial Condition.</font></div><div style="line-height:120%;padding-top:12px;text-align:left;text-indent:48px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">On </font><font style="font-family:Calibri,sans-serif;font-size:10pt;">May&#160;2, 2018</font><font style="font-family:Calibri,sans-serif;font-size:10pt;">, Exelixis, Inc. (&#8220;Exelixis&#8221;) issued a press release announcing its financial results for the quarter ended </font><font style="font-family:Calibri,sans-serif;font-size:10pt;">March&#160;30, 2018</font><font style="font-family:Calibri,sans-serif;font-size:10pt;">, and providing a corporate update. A copy of such press release is furnished herewith as Exhibit 99.1 and is incorporated herein by reference. </font></div><div style="line-height:120%;padding-top:12px;text-align:left;text-indent:48px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">The information in this report, including the exhibit hereto, shall not be deemed &#8220;filed&#8221; for purposes of Section&#160;18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended. The information contained in this report and in the accompanying exhibit shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission made by Exelixis, whether made before or after the date hereof, regardless of any general incorporation language in such filing.</font></div><div style="line-height:120%;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div style="line-height:120%;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">Item 9.01.  Financial Statements and Exhibits.</font></div><div style="line-height:120%;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div style="line-height:120%;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">(d) &#160;&#160;&#160;&#160;Exhibits.</font></div><div style="line-height:120%;text-align:left;padding-left:0px;text-indent:0px;font-size:10pt;"><div style="padding-left:0px;text-indent:0px;line-height:normal;padding-top:10px;"><table cellpadding="0" cellspacing="0" style="font-family:Times New Roman;font-size:10pt;width:59.523809523809526%;border-collapse:collapse;text-align:left;"><tr><td colspan="3"></td></tr><tr><td style="width:23%;"></td><td style="width:2%;"></td><td style="width:75%;"></td></tr><tr><td style="vertical-align:bottom;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:center;font-size:8pt;"><font style="font-family:Calibri,sans-serif;font-size:8pt;font-weight:bold;">Exhibit Number</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:center;font-size:8pt;"><font style="font-family:Calibri,sans-serif;font-size:8pt;font-weight:bold;">Exhibit Description</font></div></td></tr><tr><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;border-top:1px solid #000000;"><div style="text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">99.1</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;border-top:1px solid #000000;"><div style="font-size:10pt;"><a style="text-decoration:underline;color:#0000FF;-sec-extract:exhibit;" href="exel20180331exhibit991.htm"><font style="font-family:Calibri,sans-serif;font-size:10pt;">Press Release issued May 2, 2018.</font></a></div></td></tr></table></div></div><div style="line-height:120%;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div><br></div><div><div style="line-height:120%;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></div><hr style="page-break-after:always"><div><a name="s4B43CFF7BCF553C3B081BF4633036355"></a></div><div><div style="line-height:120%;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></div><div><br></div><div style="line-height:120%;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;font-weight:bold;">SIGNATURES </font></div><div style="line-height:120%;padding-top:12px;text-align:left;text-indent:33px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. </font></div><div style="line-height:120%;text-align:right;font-size:10pt;"><div style="padding-left:0px;text-indent:0px;line-height:normal;padding-top:10px;text-align:-moz-right;"><table cellpadding="0" cellspacing="0" style="font-family:Times New Roman;font-size:10pt;width:71.42857142857143%;border-collapse:collapse;text-align:left;margin-left:auto;margin-right:0;"><tr><td colspan="4"></td></tr><tr><td style="width:28%;"></td><td style="width:8%;"></td><td style="width:8%;"></td><td style="width:56%;"></td></tr><tr><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">E</font><font style="font-family:Calibri,sans-serif;font-size:8pt;">XELIXIS, </font><font style="font-family:Calibri,sans-serif;font-size:10pt;">I</font><font style="font-family:Calibri,sans-serif;font-size:8pt;">NC.</font></div></td></tr><tr><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;height:18px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;height:18px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;height:18px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;height:18px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td></tr><tr><td style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">May&#160;2, 2018</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="padding-bottom:1px;text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">/s/ J</font><font style="font-family:Calibri,sans-serif;font-size:8pt;">EFFREY</font><font style="font-family:Calibri,sans-serif;font-size:10pt;">&#160;J. H</font><font style="font-family:Calibri,sans-serif;font-size:8pt;">ESSEKIEL</font></div></td></tr><tr><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">Date</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;border-top:1px solid #000000;"><div style="text-align:center;font-size:8pt;"><font style="font-family:Calibri,sans-serif;font-size:8pt;font-weight:bold;">Jeffrey J. Hessekiel</font></div></td></tr><tr><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:center;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;">Executive Vice President and General Counsel</font></div></td></tr></table></div></div><div style="line-height:120%;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div><br></div><div><div style="line-height:120%;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></div>	</body>
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<div><a name="s0864C7591D6C5719A2BBD11EA071A135"></a></div><div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:654px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">&#160;&#160;&#160;&#160;</font></div><div style="line-height:120%;padding-top:12px;text-align:left;text-indent:654px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#ff0000;font-weight:bold;">&#160;&#160;&#160;&#160;</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div></div><div><br></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;"><img src="image0a05.jpg" alt="image0a05.jpg" style="height:60px;width:177px;"></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">Contacts:</font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;">Chris Senner</font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;">Chief Financial Officer</font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;">Exelixis, Inc.</font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;">650-837-7240</font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#006ebf;font-style:italic;text-decoration:underline;">csenner@exelixis.com</font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;">Susan Hubbard</font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;">EVP, Public Affairs &amp; Investor Relations</font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;">Exelixis, Inc.</font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;">650-837-8194</font></div><div style="line-height:120%;padding-top:0px;text-align:right;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#006ebf;font-style:italic;text-decoration:underline;">shubbard@exelixis.com</font></div><div style="line-height:120%;padding-top:12px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">EXELIXIS </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">ANNOUNCES FIRST QUARTER 2018 FINANCIAL </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">RESULTS AND PROVIDES CORPORATE UPDATE</font></div><div style="line-height:120%;padding-top:12px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">- Total Revenues of </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">$212.3 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">&#32;-</font></div><div style="line-height:120%;padding-top:4px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">- Cabozantinib Franchise Net Product Revenues of </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">$134.3 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">&#32;-</font></div><div style="line-height:120%;padding-top:4px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">- Net Income of </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">$115.9 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">, Diluted EPS of </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">$0.37</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">&#32;-</font></div><div style="line-height:120%;padding-top:4px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-style:italic;font-weight:bold;">- Conference Call and Webcast Today at 5:00 PM Eastern Time -</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">SOUTH SAN FRANCISCO, CA - </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">May&#160;2, 2018</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;- Exelixis, Inc. (Nasdaq: EXEL) today reported financial results for the first quarter of 2018 and provided an update on progress toward fulfilling its key corporate objectives, as well as commercial and clinical development milestones.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#8220;In the first quarter of 2018, Exelixis continued to make significant progress in the ongoing commercialization of CABOMETYX&#174; (cabozantinib) for advanced renal cell carcinoma. Following FDA approval for its expanded indication in advanced </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">first-line renal cell carcinoma</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, our team immediately began promoting CABOMETYX across all lines of therapy for this patient population, resulting in further uptake from prescribers at both major academic institutions and in the community setting,&#8221; said Michael M. Morrissey, Ph.D., President and Chief Executive Officer of Exelixis. &#8220;The resulting growth in U.S. sales, as well as the increasing collaboration revenues from our various partners, were important contributors to our strong financial performance during the quarter, leading to net income of </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$115.9 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;or </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$0.37</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;per share on a fully diluted basis.&#8221;</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">Dr. Morrissey continued: &#8220;From its initial approval for a rare disease indication five years ago, cabozantinib has grown to become an oncology franchise with the potential for global impact. We and our collaboration partners are committed to maximizing its opportunity to help patients across multiple tumor types. This now includes our recent regulatory submissions for previously treated advanced hepatocellular carcinoma, an aggressive cancer with worldwide relevance. Our efforts in liver cancer, as well as our plans to start additional phase 3 trials in other forms of cancer later this year, are each reflective of the Exelixis corporate mission to help patients with cancer recover stronger and live longer.&#8221;</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;text-decoration:underline;">First Quarter 2018 Financial Results</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Total revenues </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">for the quarter ended </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">March&#160;31, 2018</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;were </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$212.3 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, compared to </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$80.9 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;for the comparable period in </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">2017</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">. </font></div><div><br></div><div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div></div><hr style="page-break-after:always"><div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">Exelixis Announces First Quarter 2018 Financial Results&#160;&#160;&#160;&#160;Page </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">2</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">&#32;of 8</font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">and Provides Corporate Update&#160;&#160;&#160;&#160;May 2, 2018</font></div></div><div><br></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">Total revenues include net product revenues of </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$134.3 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;for the quarter ended </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">March&#160;31, 2018</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, compared to </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$68.9 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;for the comparable period in </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">2017</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">. The increase in net product revenues reflects </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">the growth of our second and later-line advanced renal cell carcinoma (RCC) business and the impact of additional sales following the U.S. Food and Drug Administration&#8217;s (FDA) approval in December 2017 of the expanded indication for CABOMETYX</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, which now</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;encompass all patients with advanced RCC.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">Total revenues also include collaboration revenues of </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$78.1 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;for the quarter ended March&#160;31, 2018 compared to </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$12.0 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;for the comparable period in 2017. The increase in collaboration revenues for the quarter ended March 31, 2018 was primarily the result of recording $45.8 million in revenue for a $50.0 million milestone from Ipsen Pharma SAS (Ipsen) we expect to earn in the second quarter of 2018 for the approval of cabozantinib for the first-line treatment of advanced RCC by the European Commission (EC). The determination to recognize the $45.8 million in revenue was made following the Committee for Medicinal Products for Human Use&#8217;s (CHMP) positive opinion of cabozantinib for the first-line treatment of advanced RCC. </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">The increase in collaboration </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">revenues </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">was also a result of a </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$20.0 million milestone from our collaboration partner Daiichi Sankyo Company, Limited (Daiichi Sankyo), which was earned as a result of Daiichi Sankyo&#8217;s submission of a regulatory application to the Japanese Pharmaceutical and Medical Devices Agency for esaxerenone (CS-3150) as a treatment for patients with essential hypertension. These increases were partially offset by a decrease in the recognition of deferred revenue due to our adoption of Accounting Standards Update No. 2014-09 </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-style:italic;">Revenue from Contracts with Customers (Accounting Standards Codification Topic 606)</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;on January 1, 2018. As a result, </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$258.5 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;was recorded in stockholders&#8217; equity relating primarily to a reduction in the remaining unrecognized upfront and non-substantive milestone payments that had been received from our collaboration partners and was included in deferred revenue at December 31, 2017. For more information on our adoption of the new revenue standard, see &#8220;Note 1. Organization and Summary of Significant Accounting Policies - Revenue&#8221; contained in Part I, Item 1 of Exelixis&#8217; Quarterly Report on Form 10-Q expected to be filed with the&#160;Securities and Exchange Commission (SEC)&#160;on&#160;May&#160;2, 2018. </font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Research and development expenses</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;for the quarter ended </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">March&#160;31, 2018</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;were </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$37.8 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, compared to </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$23.2 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;for the comparable period in </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">2017</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">. The increase in research and development expenses was primarily related to an increase in personnel-related expenses resulting from an increase in headcount in support of our development and discovery efforts and an increase in clinical trial costs. Clinical trial costs increased primarily due to start-up costs associated with CheckMate 9ER, an ongoing phase 3 pivotal trial of cabozantinib plus immunotherapy in patients with previously untreated RCC that is being conducted with Bristol-Myers Squibb Company, and start-up costs associated with our phase 1b trial of cabozantinib and atezolizumab in locally advanced or metastatic solid tumors; those increases were partially offset by decreases in costs related to METEOR, our completed phase 3 pivotal trial comparing CABOMETYX to everolimus in patients with advanced RCC. Research and development expenses for the quarter ended </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">March&#160;31, 2018</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;also included a $3.0 million upfront payment for our exclusive collaboration and license agreement with&#160;StemSynergy Therapeutics, Inc. (StemSynergy).</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Selling, general and administrative expenses</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;for the quarter ended </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">March&#160;31, 2018</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;were </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$52.6 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, compared to </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$34.3 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;for the comparable period in </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">2017</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">. The increase in selling, general and administrative expenses was primarily a result of increases in corporate giving, personnel expenses and marketing activities. The increase in personnel expense resulted from an increase in general and administrative headcount to support the company&#8217;s commercial and research and development organizations. </font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Net income </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">for the quarter ended </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">March&#160;31, 2018</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;was </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$115.9 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, or </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$0.39</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;per share, basic and </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$0.37</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;per share, diluted, compared to a </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$16.7 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, or </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$0.06</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;per share, basic and </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$0.05</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;per share diluted, for the comparable period in </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">2017</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">. The increase in net income was primarily the result of increases in net </font></div><div><br></div><div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div></div><hr style="page-break-after:always"><div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">Exelixis Announces First Quarter 2018 Financial Results&#160;&#160;&#160;&#160;Page </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">3</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">&#32;of 8</font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">and Provides Corporate Update&#160;&#160;&#160;&#160;May 2, 2018</font></div></div><div><br></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">product revenues and collaboration revenues, which was partially offset by the increases in research and development and selling, general and administrative expenses.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Cash and cash equivalents, short- and long-term investments and short- and long-term restricted cash and investments </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">totaled </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$525.6 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;at </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">March&#160;31, 2018</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, as compared to </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$457.2 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;at </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">December&#160;31, 2017</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;text-decoration:underline;">2018 Financial Guidance </font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">The company is maintaining its guidance that total costs and operating expenses for the full year will be between $430 million and $460 million.&#160;This guidance includes approximately $50 million of non-cash costs and expenses related primarily to stock-based compensation expense. </font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;text-decoration:underline;">Cabozantinib Highlights</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Strong Growth in Cabozantinib Franchise Net Revenues.</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#160;Cabozantinib generated </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$134.3 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;in net product revenues during the first quarter of 2018, an increase of </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">95 percent</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;year-over-year. During the first quarter of 2018,&#160;CABOMETYX generated </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$128.9 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;in net product revenues and COMETRIQ&#174; (cabozantinib) capsules for the treatment of patients with progressive, metastatic medullary thyroid cancer generated an additional </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">$5.3 million</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;in net product revenues.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Amendment to Clinical Research Protocol for Phase 1b Trial of Cabozantinib in Combination with Atezolizumab in Patients with Locally Advanced or Metastatic Solid Tumors.</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;In January, Exelixis announced an amendment to the protocol for the phase 1b trial of cabozantinib in combination with atezolizumab in patients with locally advanced or metastatic solid tumors. The amendment added four new expansion cohorts to the trial, which now includes patients with non-small cell lung cancer and castration-resistant prostate cancer, in addition to previously included patients with RCC and urothelial carcinoma (UC). The primary objective in the expansion stage of this trial remains to determine the objective response rate in each cohort.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Cabozantinib Data at the ASCO 2018 Genitourinary Cancers Symposium (ASCO-GU).</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;In February, cabozantinib was the subject of 14 presentations at the 2018 ASCO-GU Symposium in San Francisco. Updated results from the ongoing phase 1 trial of cabozantinib in combination with nivolumab, with or without ipilimumab, in patients with refractory genitourinary tumors were the subject of a poster presentation, with the two combination regimens demonstrating an acceptable tolerability profile, and high rates of durable responses in the previously treated metastatic UC and metastatic RCC cohorts. This phase 1 trial informed the design of CheckMate 9ER.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Cabozantinib Data at the 2018 Multidisciplinary Head and Neck Cancers Symposium.</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;Also in February, cabozantinib was the subject of an oral presentation at this medical meeting held in Scottsdale, Arizona. Investigators presented results from the ongoing investigator-sponsored phase 2 trial of cabozantinib in patients with radioiodine-refractory differentiated thyroid carcinoma (DTC) in the first-line setting. </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">Based on these results and data from other studies of cabozantinib in previously treated DTC</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">,</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;Exelixis plans to initiate a pivotal phase 3 study with cabozantinib in patients with advanced DTC later this year.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Submission of Supplemental New Drug Application (sNDA) for CABOMETYX as a Treatment for Patients with Previously Treated Advanced Hepatocellular Carcinoma (HCC). </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">In March, Exelixis announced it had completed the submission of its sNDA to the FDA for CABOMETYX as a treatment for patients with previously treated advanced HCC. The sNDA submission is based on results from the CELESTIAL randomized pivotal phase 3 trial, data from which were presented in January at the American Society of Clinical Oncology 2018 Gastrointestinal Cancers Symposium (ASCO-GI).</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">&#32;</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">At ASCO-GI, Exelixis and Ipsen hosted a live briefing event </font></div><div><br></div><div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div></div><hr style="page-break-after:always"><div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">Exelixis Announces First Quarter 2018 Financial Results&#160;&#160;&#160;&#160;Page </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">4</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">&#32;of 8</font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">and Provides Corporate Update&#160;&#160;&#160;&#160;May 2, 2018</font></div></div><div><br></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">for the financial community to discuss cabozantinib data presented at the conference. The replay of the briefing is available on the News &amp; Events / Event Calendar page at </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#006ebf;font-style:italic;text-decoration:underline;">www.exelixis.com</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">European Medicines Agency (EMA) Validation of the Application for a New Indication for CABOMETYX for Previously Treated Advanced HCC. </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">Also in March, Exelixis&#8217; partner Ipsen announced its application for variation to the CABOMETYX marketing authorization had been validated by the EMA for the addition of a new indication for patients with previously treated advanced HCC. Upon the acceptance of this filing, Exelixis will receive a $10.0 million milestone payment per the terms of the company&#8217;s collaboration agreement with Ipsen. </font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">CABOMETYX Receives Positive CHMP Opinion for Previously Untreated Intermediate- or Poor-Risk Advanced RCC. </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">In March, Exelixis&#8217; partner Ipsen received a positive opinion from the CHMP, the scientific committee of the EMA, for CABOMETYX for the first-line treatment of adults with intermediate- or poor-risk advanced RCC. The positive CHMP opinion is being reviewed by the EC, which has the authority to approve medicines for the European Union.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;text-decoration:underline;">Cobimetinib Highlights</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Phase 1b Results for the Combination of Cobimetinib and Atezolizumab in Metastatic Colorectal Cancer (CRC) at ASCO-GI.</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;In January, updated safety and efficacy results from the phase 1b clinical trial sponsored by Genentech, Inc. (a member of the Roche Group) (Genentech) evaluating cobimetinib in combination with atezolizumab in patients with metastatic CRC were presented at ASCO-GI. Initial results reported from this study presented at the 2016 ASCO Annual Meeting led to the initiation of IMblaze370 (formerly COTEZO), a phase 3 pivotal trial evaluating both the combination of cobimetinib and atezolizumab and atezolizumab alone versus regorafenib in patients with unresectable locally advanced or metastatic CRC, for which Genentech has guided it expects top-line results in the first half of 2018.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">IMspire150 TRILOGY Trial Reaches Full Enrollment.</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;The Roche Group recently confirmed that IMspire150 TRILOGY, its phase 3 pivotal trial evaluating the combination of cobimetinib, atezolizumab and vemurafenib in patients with first-line BRAF V600 mutation-positive metastatic or unresectable locally advanced melanoma, completed enrollment. The trial began enrolling patients in January 2017.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;text-decoration:underline;">Corporate Highlights</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Exclusive Licensing Agreement with StemSynergy for the Discovery and Development of Novel Anticancer Therapies.</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;In January, Exelixis announced it had entered into an exc</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">lusive collaboration and license agreement with StemSynergy for the discovery and development of novel oncology compounds targeting Casein Kinase 1 alpha</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, a component of the Wnt signaling pathway implicated in key oncogenic processes.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Daiichi Sankyo&#8217;s Submission of Regulatory Filing for Esaxerenone (CS-3150) in Japan. </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">In February, Exelixis announced its partner Daiichi Sankyo submitted its regulatory application for esaxerenone as a treatment for patients with hypertension to the Japanese Pharmaceutical and Medical Devices Agency. The application was based on the results of phase 3 studies including ESAX-HTN, a randomized, double-blind, three-arm parallel group comparison study evaluating the efficacy and safety of esaxerenone versus eplerenone in patients with essential hypertension in Japan. As a result of the submission, Exelixis received a $20.0 million milestone payment in March 2018 per the collaboration agreement.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;">Election of Dr. Maria Freire to Exelixis&#8217; Board of Directors. </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">In April, Exelixis announced the election of biomedical research executive Maria C. Freire, Ph.D. to the company&#8217;s Board of Directors. Dr. Freire currently serves as President and Executive Director and as a member of the board of directors of the Foundation for the National Institutes of Health, an independent 501(c)(3) charitable organization established by </font></div><div><br></div><div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div></div><hr style="page-break-after:always"><div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">Exelixis Announces First Quarter 2018 Financial Results&#160;&#160;&#160;&#160;Page </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">5</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">&#32;of 8</font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">and Provides Corporate Update&#160;&#160;&#160;&#160;May 2, 2018</font></div></div><div><br></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">Congress to support the National Institutes of Health by raising private funds for biomedical research and fostering partnerships and alliances around the world.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;text-decoration:underline;">Basis of Presentation</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">Exelixis has adopted a 52- or 53-week fiscal year that generally ends on the Friday closest to December 31</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;"><sup style="vertical-align:top;line-height:120%;font-size:pt">st</sup></font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">. For convenience, references in this press release as of and for the fiscal periods ended&#160;March 30, 2018, December 29, 2017 and March 31, 2017&#160;are indicated as being as of and for the periods ended&#160;March 31, 2018, December 31, 2017 and March 31, 2017, respectively. </font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;text-decoration:underline;">Conference Call and Webcast</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">Exelixis management will discuss the company&#8217;s financial results for the first quarter of 2018 and provide a general business update during a conference call beginning at 5:00 p.m. ET / 2:00 p.m. PT today, Wednesday, May 2, 2018.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">To access the webcast link, log onto </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#006ebf;font-style:italic;text-decoration:underline;">www.exelixis.com</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">and proceed to the News &amp; Events / Event Calendar page under the Investors &amp; Media heading. Please connect to the company&#8217;s website at least 15 minutes prior to the conference call to ensure adequate time for any software download that may be required to listen to the webcast. Alternatively, please call </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#006ebf;text-decoration:underline;">855-793-2457</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;(domestic) or </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#006ebf;text-decoration:underline;">631-485-4921</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;(international) and provide the conference call passcode </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">7895176</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;to join by phone.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">A telephone replay will be available until 8:30 p.m. EDT on May 4, 2018. Access numbers for the telephone replay are: </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#006ebf;text-decoration:underline;">855-859-2056</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;(domestic) and&#160;</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#006ebf;text-decoration:underline;">404-537-3406</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;(international); the passcode is </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">7895176</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">. A webcast replay will also be archived on </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#006ebf;font-style:italic;text-decoration:underline;">www.exelixis.com</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">&#32;for one year.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;text-decoration:underline;">About Exelixis</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">Founded in 1994, Exelixis, Inc. (Nasdaq: EXEL) is a commercially successful, oncology-focused biotechnology company that strives to accelerate the discovery, development and commercialization of new medicines for difficult-to-treat cancers. Following early work in model genetic systems, we established a broad drug discovery and development platform that has served as the foundation for our continued efforts to bring new cancer therapies to patients in need. We discovered our lead compounds, cabozantinib and cobimetinib, and advanced them into clinical development before entering into partnerships with leading biopharmaceutical companies in our efforts to bring these medicines to patients globally. We are steadfast in our commitment to prudently reinvest in our business to maximize the potential of our pipeline. We intend to supplement our existing therapeutic assets with targeted business development activities and internal drug discovery - all to deliver the next generation of Exelixis medicines and help patients recover stronger and live longer. Exelixis recently earned a spot on Deloitte&#8217;s Technology Fast 500 list, a yearly award program honoring the 500 fastest-growing companies over the past four years. For more information about Exelixis, please visit </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#006ebf;font-style:italic;text-decoration:underline;">www.exelixis.com</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">, follow @ExelixisInc on Twitter or like Exelixis, Inc. on Facebook.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;font-weight:bold;text-decoration:underline;">Forward-Looking Statements </font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">This press release contains forward-looking statements, including, without limitation, statements related to: the potential for cabozantinib to become an oncology franchise with global impact and Exelixis&#8217; commitment to maximizing its opportunity to help patients across multiple tumor types; Exelixis&#8217; plans to conduct future clinical studies; </font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">Exelixis&#8217; expectations&#160;related to the receipt of&#160;milestone payments in connection with the EC&#8217;s approval of cabozantinib as a first-line treatment of advanced RCC&#160;and the EMA&#8217;s validation of Ipsen&#8217;s application for variation to the CABOMETYX marketing authorization for the added indication of patients with previously treated advanced HCC</font><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">; Exelixis&#8217; guidance for 2018 total costs and operating expenses, including non-cash costs and expenses; Exelixis&#8217; plans to initiate a pivotal phase 3 study </font></div><div><br></div><div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div></div><hr style="page-break-after:always"><div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">Exelixis Announces First Quarter 2018 Financial Results&#160;&#160;&#160;&#160;Page </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">6</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">&#32;of 8</font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">and Provides Corporate Update&#160;&#160;&#160;&#160;May 2, 2018</font></div></div><div><br></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;color:#000000;">with cabozantinib in patients with advanced DTC later this year; Exelixis&#8217; expectation of top-line results in the first half of 2018 from the phase 3 pivotal trial of cobimetinib in combination with Genentech&#8217;s atezolizumab in advanced CRC; Exelixis&#8217; plans to reinvest in its business to maximize the potential of the company&#8217;s pipeline, including through targeted business development activities and internal drug discovery; and Exelixis&#8217; mission to deliver the next generation of&#160;Exelixis&#160;medicines and help patients recover stronger and live longer. Words such as &#8220;focused,&#8221; &#8220;mission,&#8221; &#8220;future,&#8221; &#8220;expect,&#8221; &#8220;plans,&#8221; &#8220;committed,&#8221; &#8220;will,&#8221; &#8220;guidance,&#8221; &#8220;commitment,&#8221; &#8220;potential,&#8221; &#8220;intend,&#8221; or other similar expressions identify forward-looking statements, but the absence of these words does not necessarily mean that a statement is not forward-looking. In addition, any statements that refer to expectations, projections or other characterizations of future events or circumstances are forward-looking statements. These forward-looking statements are based upon Exelixis&#8217; current plans, assumptions, beliefs, expectations, estimates and projections. Forward-looking statements involve risks and uncertainties. Actual results and the timing of events could differ materially from those anticipated in the forward-looking statements as a result of these risks and uncertainties, which include, without limitation: the degree of market acceptance of CABOMETYX, COMETRIQ and COTELLIC and the availability of sufficient coverage and adequate reimbursement for these products; risks and uncertainties related to regulatory review and approval processes and Exelixis&#8217; compliance with applicable legal and regulatory requirements; risks related to the potential failure of cabozantinib and cobimetinib, both alone and in combination with other therapies, to demonstrate safety and efficacy in clinical testing; the availability of data at the referenced times; Exelixis&#8217; dependence on its relationship with&#160;its collaboration partners, including the level of their investment in the resources necessary to successfully commercialize partnered compounds in the territories where they are approved;&#160;Exelixis&#8217; ability and the ability of its collaborators to conduct clinical trials of cabozantinib and cobimetinib, both alone and in combination with other therapies, sufficient to achieve a positive completion; the level of costs associated with Exelixis&#8217; commercialization, research and development, in-licensing or acquisition of product candidates, and other activities; Exelixis&#8217;&#160;dependence on third-party vendors for the development, manufacture and supply of its product; Exelixis&#8217; ability to protect its intellectual property rights; market competition, including the potential for competitors to obtain approval for generic versions of Exelixis&#8217; marketed products; changes in economic and business conditions, and other factors discussed under the caption &#8220;Risk Factors&#8221; in Exelixis&#8217; Annual Report on Form 10-K filed with the&#160;SEC on&#160;February 26, 2018, and in Exelixis&#8217; future filings with the&#160;SEC, including, without limitation, Exelixis&#8217; Quarterly Report on Form 10-Q expected to be filed with the&#160;SEC&#160;on&#160;May 2, 2018. The forward-looking statements made in this press release speak only as of the date of this press release.&#160;Exelixis&#160;expressly disclaims any duty, obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in Exelixis&#8217; expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based.</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div><div style="line-height:120%;padding-top:12px;text-align:center;padding-left:0px;text-indent:0px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;color:#000000;font-style:italic;">Exelixis, the Exelixis logo, CABOMETYX, COMETRIQ and COTELLIC are registered U.S. trademarks.</font></div><div style="line-height:120%;padding-top:12px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">-see attached financial tables-</font></div><div><br></div><div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div></div><hr style="page-break-after:always"><div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">Exelixis Announces First Quarter 2018 Financial Results&#160;&#160;&#160;&#160;Page </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">7</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">&#32;of 8</font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">and Provides Corporate Update&#160;&#160;&#160;&#160;May 2, 2018</font></div></div><div><br></div><div style="line-height:120%;padding-top:0px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">EXELIXIS, INC.</font></div><div style="line-height:120%;padding-top:0px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS</font></div><div style="line-height:120%;padding-top:0px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">(in thousands, except per share data)</font></div><div style="line-height:120%;padding-top:0px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">(unaudited)</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:0px;text-align:center;font-size:11pt;"><div style="padding-left:0px;text-indent:0px;line-height:normal;padding-top:10px;"><table cellpadding="0" cellspacing="0" style="font-family:Times New Roman;font-size:10pt;margin-left:auto;margin-right:auto;width:100%;border-collapse:collapse;text-align:left;"><tr><td colspan="8"></td></tr><tr><td style="width:71%;"></td><td style="width:1%;"></td><td style="width:12%;"></td><td style="width:1%;"></td><td style="width:1%;"></td><td style="width:1%;"></td><td style="width:12%;"></td><td style="width:1%;"></td></tr><tr><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="7" style="vertical-align:bottom;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:center;font-size:9pt;"><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;font-style:normal;font-weight:bold;text-decoration:none;">Three Months Ended March 31,</font></div></td></tr><tr><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="3" style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;border-top:1px solid #000000;"><div style="text-align:center;font-size:9pt;"><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;font-style:normal;font-weight:bold;text-decoration:none;">2018</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;border-top:1px solid #000000;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="3" style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;border-top:1px solid #000000;"><div style="text-align:center;font-size:9pt;"><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;font-style:normal;font-weight:bold;text-decoration:none;">2017</font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Revenues:</font></div></td><td colspan="3" style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="3" style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td></tr><tr><td style="vertical-align:middle;padding-left:20px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Net product revenues</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">134,272</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">68,877</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:20px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Collaboration revenues</font></div></td><td colspan="2" style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">78,074</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">12,010</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;padding-left:36px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Total revenues</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;border-top:1px solid #000000;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">212,346</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;border-top:1px solid #000000;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;border-top:1px solid #000000;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">80,887</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;border-top:1px solid #000000;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Operating expenses:</font></div></td><td colspan="3" style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="3" style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td></tr><tr><td style="vertical-align:middle;padding-left:20px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Cost of goods sold</font></div></td><td colspan="2" style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">5,639</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">3,203</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:20px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Research and development</font></div></td><td colspan="2" style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">37,757</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">23,210</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;padding-left:20px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Selling, general and administrative</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">52,643</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">34,288</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:36px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Total operating expenses</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">96,039</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">60,701</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Income from operations</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">116,307</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">20,186</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Other income (expense), net:</font></div></td><td colspan="3" style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="3" style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td></tr><tr><td style="vertical-align:middle;padding-left:20px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Interest income</font></div></td><td colspan="2" style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">1,895</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">1,113</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:20px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Interest expense</font></div></td><td colspan="2" style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">&#8212;</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">(4,420</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-right:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">)</font></div></td></tr><tr><td style="vertical-align:middle;padding-left:20px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Other, net</font></div></td><td colspan="2" style="vertical-align:bottom;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">169</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:bottom;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">(45</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;padding-right:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">)</font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:36px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Total other income (expense), net</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">2,064</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">(3,352</font></div></td><td style="vertical-align:middle;border-bottom:1px solid #000000;background-color:#cceeff;padding-right:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">)</font></div></td></tr><tr><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Income before income taxes</font></div></td><td colspan="2" style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">118,371</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">16,834</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Provision for income taxes</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">2,514</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;border-bottom:1px solid #000000;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">134</font></div></td><td style="vertical-align:bottom;border-bottom:1px solid #000000;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;padding-left:12px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;text-indent:24px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Net income</font></div></td><td style="vertical-align:middle;border-bottom:3px double #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;border-bottom:3px double #000000;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">115,857</font></div></td><td style="vertical-align:bottom;border-bottom:3px double #000000;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:middle;border-bottom:3px double #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;border-bottom:3px double #000000;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">16,700</font></div></td><td style="vertical-align:bottom;border-bottom:3px double #000000;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Net income per share, basic</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;background-color:#cceeff;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">0.39</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;background-color:#cceeff;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">0.06</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Net income per share, diluted</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">0.37</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">0.05</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Shares used in computing net income per share, basic </font></div></td><td colspan="2" style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">296,421</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">290,870</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Shares used in computing net income per share, diluted</font></div></td><td colspan="2" style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">313,691</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="2" style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">309,535</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr></table></div></div><div><br></div><div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div></div><hr style="page-break-after:always"><div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;"><br></font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">Exelixis Announces First Quarter 2018 Financial Results&#160;&#160;&#160;&#160;Page </font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">8</font><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">&#32;of 8</font></div><div style="line-height:120%;padding-top:0px;text-align:left;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">and Provides Corporate Update&#160;&#160;&#160;&#160;May 2, 2018</font></div></div><div><br></div><div style="line-height:120%;padding-top:0px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">EXELIXIS, INC.</font></div><div style="line-height:120%;padding-top:0px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;font-weight:bold;">CONDENSED CONSOLIDATED BALANCE SHEET DATA</font></div><div style="line-height:120%;padding-top:0px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">(in thousands)</font></div><div style="line-height:120%;padding-top:0px;text-align:center;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">(unaudited)</font></div><div style="line-height:120%;padding-bottom:0px;padding-top:0px;text-align:center;font-size:11pt;"><div style="padding-left:0px;text-indent:0px;line-height:normal;padding-top:10px;"><table cellpadding="0" cellspacing="0" style="font-family:Times New Roman;font-size:10pt;margin-left:auto;margin-right:auto;width:100%;border-collapse:collapse;text-align:left;"><tr><td colspan="8"></td></tr><tr><td style="width:71%;"></td><td style="width:1%;"></td><td style="width:12%;"></td><td style="width:1%;"></td><td style="width:1%;"></td><td style="width:1%;"></td><td style="width:12%;"></td><td style="width:1%;"></td></tr><tr><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="3" style="vertical-align:bottom;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:center;font-size:9pt;"><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;font-style:normal;font-weight:bold;text-decoration:none;">March&#160;31, <br>2018</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td colspan="3" style="vertical-align:bottom;border-bottom:1px solid #000000;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:center;text-indent:2px;font-size:9pt;"><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;font-style:normal;font-weight:bold;text-decoration:none;">December 31, 2017 </font><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;font-style:normal;font-weight:bold;text-decoration:none;"><sup style="vertical-align:top;line-height:120%;font-size:pt">(1)</sup></font></div></td></tr><tr><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Cash and investments </font><font style="font-family:Calibri,sans-serif;font-size:11pt;"><sup style="vertical-align:top;line-height:120%;font-size:pt">(2)</sup></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;background-color:#cceeff;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">525,634</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;background-color:#cceeff;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">457,176</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Working capital</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">480,821</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">369,704</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Total assets</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;background-color:#cceeff;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;background-color:#cceeff;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">774,915</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;background-color:#cceeff;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;background-color:#cceeff;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;background-color:#cceeff;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">655,294</font></div></td><td style="vertical-align:bottom;background-color:#cceeff;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr><tr><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">Total stockholders&#8217; equity</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">669,766</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td><td style="vertical-align:bottom;padding-left:2px;padding-top:2px;padding-bottom:2px;padding-right:2px;"><div style="overflow:hidden;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">&#160;</font></div></td><td style="vertical-align:middle;padding-left:2px;padding-top:2px;padding-bottom:2px;"><div style="text-align:left;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">$</font></div></td><td style="vertical-align:middle;padding-top:2px;padding-bottom:2px;"><div style="text-align:right;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;">284,961</font></div></td><td style="vertical-align:bottom;"><div style="text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"><br></font></div></td></tr></table></div></div><div style="line-height:120%;padding-bottom:0px;padding-top:0px;text-align:left;padding-left:48px;text-indent:-24px;font-size:9pt;"><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">_______________________________________</font></div><table cellpadding="0" cellspacing="0" style="padding-top:0px;padding-bottom:0px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:48px;"></td><td></td></tr><tr><td style="vertical-align:top"><div style="line-height:120%;font-size:9pt;padding-left:24px;"><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">&#32;(1)</font></div></td><td style="vertical-align:top;"><div style="line-height:120%;text-align:left;font-size:9pt;"><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">Derived from the audited consolidated financial statements.</font></div></td></tr></table><table cellpadding="0" cellspacing="0" style="padding-top:0px;padding-bottom:0px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:48px;"></td><td></td></tr><tr><td style="vertical-align:top"><div style="line-height:120%;font-size:9pt;padding-left:24px;"><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">&#32;(2)</font></div></td><td style="vertical-align:top;"><div style="line-height:120%;text-align:left;font-size:9pt;"><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">Cash and investments include cash and cash equivalents, short- and long-term investments and short- and long-term restricted cash and investments. Short- and long-term restricted cash and investments totaled </font><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">$2.0 million</font><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">&#32;as of </font><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">March&#160;31, 2018</font><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">&#32;and </font><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">$5.2 million</font><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">&#32;as of </font><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">December&#160;31, 2017</font><font style="font-family:Calibri,sans-serif;font-size:9pt;color:#000000;">.</font></div></td></tr></table><div style="line-height:120%;padding-top:12px;text-align:center;padding-left:0px;text-indent:0px;font-size:10pt;"><font style="font-family:Calibri,sans-serif;font-size:10pt;color:#000000;"># # #</font></div><div><br></div><div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div><div style="line-height:120%;padding-bottom:0px;padding-top:12px;text-align:justify;padding-left:0px;text-indent:0px;font-size:11pt;"><font style="font-family:Calibri,sans-serif;font-size:11pt;"><br></font></div></div>	</body>
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##__9

end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
