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Revenues (Revenues by Disaggregated Category) (Details) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 28, 2018 | Sep. 28, 2018 | Jun. 29, 2018 | Mar. 30, 2018 | Dec. 29, 2017 | Sep. 30, 2017 | Jun. 30, 2017 | Mar. 31, 2017 | Dec. 28, 2018 | Dec. 29, 2017 | Dec. 30, 2016
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total revenues | $ 228,602 | $ 225,397 | $ 186,108 | $ 213,719 | $ 120,072 | $ 152,510 | $ 99,008 | $ 80,887 | $ 853,826 | $ 452,477 | $ 191,454
Net product revenues |  |  |  |  |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 619,279 | 349,008 | 135,375
Gross product revenues |  |  |  |  |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 738,529 | 402,569 | 151,499
Discounts and allowances |  |  |  |  |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 119,250 | 53,561 | 16,124
Total collaboration revenues |  |  |  |  |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 234,547 | 103,469 | 56,079
License revenues |  |  |  |  |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 192,188 | 96,637 | 56,286
Research and development services revenues |  |  |  |  |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 39,501 | 8,737 | 0
Other collaboration revenues |  |  |  |  |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | $ 2,858 | $ (1,905) | $ (207)

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