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Organization and Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 28, 2018
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
Impact of Adoption of Topic 606 and Topic 842 | The impact of the adoption of Topic 606 and Topic 842 on the accompanying Consolidated Balance Sheet as of January 1, 2018 was as follows (in thousands):
| December 31, 2017 |  | Adjustments Due to the Adoption of Topic 606 |  | Adjustments Due to the Adoption of Topic 842 |  | January 1, 2018
Contract assets: unbilled collaboration revenue, gross: |  |  |  |  |  |  |
Current portion | $ | — |  |  | $ | 9,588 |  |  | $ | — |  |  | $ | 9,588 |
Long-term portion | $ | — |  |  | $ | 12,247 |  |  | $ | — |  |  | $ | 12,247 |
Other receivables | $ | 3,892 |  |  | $ | — |  |  | $ | 7,743 |  |  | $ | 11,635 |
Property and equipment, net | $ | 25,743 |  |  | $ | — |  |  | $ | (14,530 | ) |  | $ | 11,213 |
Operating lease right-of-use assets | $ | — |  |  | $ | — |  |  | $ | 8,579 |  |  | $ | 8,579 |
Contract liabilities: deferred revenue, gross: |  |  |  |  |  |  |
Current portion | $ | 31,984 |  |  | $ | (23,591 | ) |  | $ | — |  |  | $ | 8,393 |
Long-term portion | $ | 238,520 |  |  | $ | (213,079 | ) |  | $ | — |  |  | $ | 25,441 |
Operating lease liabilities: |  |  |  |  |  |  |
Other current liabilities(1) | $ | 16,150 |  |  | $ | — |  |  | $ | 3,173 |  |  | $ | 19,323 |
Long-term portion of lease liabilities (2) | $ | 14,938 |  |  | $ | — |  |  | $ | (1,615 | ) |  | $ | 13,323 |
Accumulated deficit | $ | (1,829,172 | ) |  | $ | 258,505 |  |  | $ | 234 |  |  | $ | (1,570,433 | )
____________________ (1) Includes deferred rent and current portion of operating lease liabilities. (2) Long-term portion of operating lease liabilities and Financing obligation for build-to-suit lease. The impact of the adoption of Topic 606 and Topic 842 on the accompanying Consolidated Statements of Operations for year ended December 31, 2018 was as follows (in thousands):
| Year Ended December 31, 2018
| As Reported |  | Effect of Adoption of Topic 606 Higher / (Lower) |  | Effect of Adoption of Topic 842 Higher / (Lower) |  | Balances Without the Adoption of Topic 606 or 842
Collaboration revenues | $ | 234,547 |  |  | $ | (35,882 | ) |  | $ | — |  |  | $ | 270,429 |
Total revenues | $ | 853,826 |  |  | $ | (35,882 | ) |  | $ | — |  |  | $ | 889,708 |
Selling, general and administrative expenses | $ | 206,366 |  |  | $ | — |  |  | $ | 1,204 |  |  | $ | 205,162 |
Total operating expenses | $ | 414,971 |  |  | $ | — |  |  | $ | 1,204 |  |  | $ | 413,767 |
Interest expense | $ | — |  |  | $ | — |  |  | $ | (631 | ) |  | $ | (631 | )
Total other income (expense), net | $ | 13,237 |  |  | $ | — |  |  | $ | 631 |  |  | $ | 12,606 |
Income before income taxes | $ | 452,092 |  |  | $ | (35,882 | ) |  | $ | (573 | ) |  | $ | 488,547 |
Income tax benefit (provision) | $ | 237,978 |  |  | $ | (48,325 | ) |  | $ | 73 |  |  | $ | 286,230 |
Net income | $ | 690,070 |  |  | $ | (84,207 | ) |  | $ | (500 | ) |  | $ | 774,777 |
Net income per share, basic | $ | 2.32 |  |  | $ | (0.28 | ) |  | $ | — |  |  | $ | 2.60 |
Net income per share, diluted | $ | 2.21 |  |  | $ | (0.27 | ) |  | $ | — |  |  | $ | 2.48 |
Estimated Useful Lives of Property and Equipment | Property and equipment are recorded at cost and depreciated using the straight-line method over the following estimated useful lives once it is placed into service:
Asset Category |  | Estimated Useful Life
Lab equipment |  | 5 years
Furniture and fixtures |  | 7 years
Office equipment |  | 5 years
Computer equipment and software |  | 3 years
Leasehold improvements |  | 7 to 15 years

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