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Property and Equipment
12 Months Ended
Dec. 28, 2018
Property, Plant and Equipment [Abstract]  
Property and Equipment
PROPERTY AND EQUIPMENT
Property and equipment were as follows (in thousands): 
 
December 31,
2018
 
December 31,
2017
Leasehold improvements
$
33,941

 
$
4,715

Computer equipment and software
15,022

 
14,146

Furniture and fixtures
12,709

 
1,609

Laboratory equipment
5,668

 
5,959

Construction in progress
866

 
22,114

 
68,206

 
48,543

Less: accumulated depreciation and amortization
(17,309
)
 
(22,800
)
Property and equipment, net
$
50,897

 
$
25,743


Depreciation expense was $4.9 million, $1.2 million and $1.0 million during the years ended December 31, 2018, 2017 and 2016, respectively.
In May 2017, we entered into the Lease for office and research facilities located at 1851, 1801, and 1751 Harbor Bay Parkway, Alameda, California (the Premises). The Lease was amended in October 2017 and June 2018 to increase the space leased to an aggregate of 134,765 square feet. For a description of the Lease, see “Note 11. Commitments.” In June 2018, we relocated our offices and research facilities to the Premises. Accordingly, we placed into service $46.3 million in related Leasehold improvements, Furniture and fixtures and Computer equipment and software, portions of which were included in Construction in progress at prior period ends.