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Stock-based Compensation (Tables)
12 Months Ended
Dec. 28, 2018
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of Allocated Employee Stock-Based Compensation Expense
We allocated the stock-based compensation expense for our equity incentive plans and our 2000 Employee Stock Purchase Plan (ESPP) as follows (in thousands):
 
Year Ended December 31,
 
2018
 
2017
 
2016
Research and development
$
13,115

 
$
7,569

 
$
9,366

Selling, general and administrative
27,511

 
16,369

 
13,546

Total stock-based compensation
$
40,626

 
$
23,938

 
$
22,912

Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
The weighted average grant-date fair value per share of stock options and ESPP purchases was as follows:
 
Year Ended December 31,
 
2018
 
2017
 
2016
Stock options
$
9.07

 
$
11.42

 
$
4.77

ESPP
$
6.40

 
$
6.00

 
$
2.17

Schedule of Fair Value of Employee Share-Based Payments Awards Stock Option Assumptions and Weighted Average Fair Values
The grant-date fair value of stock option grants and ESPP purchases was estimated using the following assumptions:
 
Year Ended December 31,
 
2018
 
2017
 
2016
Stock options:
 
 
 
 
 
Risk-free interest rate
2.81
%
 
1.98
%
 
1.15
%
Dividend yield
%
 
%
 
%
Volatility
55
%
 
59
%
 
76
%
Expected life
4.4 years

 
4.5 years

 
4.4 years

ESPP:
 
 
 
 
 
Risk-free interest rate
1.93
%
 
1.09
%
 
0.55
%
Dividend yield
%
 
%
 
%
Volatility
53
%
 
58
%
 
65
%
Expected life
6 months

 
6 months

 
6 months

Schedule of Fair Value of Employee Share-Based Payments Awards ESPP Assumptions and Weighted Average Fair Values
The grant-date fair value of stock option grants and ESPP purchases was estimated using the following assumptions:
 
Year Ended December 31,
 
2018
 
2017
 
2016
Stock options:
 
 
 
 
 
Risk-free interest rate
2.81
%
 
1.98
%
 
1.15
%
Dividend yield
%
 
%
 
%
Volatility
55
%
 
59
%
 
76
%
Expected life
4.4 years

 
4.5 years

 
4.4 years

ESPP:
 
 
 
 
 
Risk-free interest rate
1.93
%
 
1.09
%
 
0.55
%
Dividend yield
%
 
%
 
%
Volatility
53
%
 
58
%
 
65
%
Expected life
6 months

 
6 months

 
6 months


Summary of All Stock Option Activity
Activity for stock options during the year ended December 31, 2018 was as follows (dollars in thousands, except per share amounts):
 
Shares
 
Weighted 
Average
Exercise Price
 
Weighted 
Average
Remaining
Contractual
Term
 
Aggregate
Intrinsic
Value
Stock options outstanding at December 31, 2017
22,208,446

 
$
6.83

 
 
 
 
Granted
3,238,473

 
$
19.40

 
 
 
 
Exercised
(2,466,579
)
 
$
4.90

 
 
 
 
Forfeited
(288,197
)
 
$
15.71

 
 
 
 
Expired
(18,081
)
 
$
20.64

 
 
 
 
Stock options outstanding at December 31, 2018
22,674,062

 
$
8.71

 
3.7 years
 
$
254,201

Exercisable at December 31, 2018
16,463,202

 
$
5.65

 
3.0 years
 
$
229,699

Summary of All RSU Activity
Activity for RSUs during the year ended December 31, 2018 was as follows (dollars in thousands, except per share amounts):
 
Shares
 
Weighted 
Average
Grant Date
Fair Value
 
Weighted 
Average
Remaining
Contractual 
Term
 
Aggregate
Intrinsic
Value
RSUs outstanding at December 31, 2017
3,762,990

 
$
17.76

 
 
 
 
Awarded
2,519,425

 
$
18.46

 
 
 
 
Vested and released
(1,081,339
)
 
$
16.05

 
 
 
 
Forfeited
(343,742
)
 
$
18.99

 
 
 
 
RSUs outstanding at December 31, 2018
4,857,334

 
$
18.42

 
2.1 years
 
$
94,427