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Organization and Summary of Significant Accounting Policies (Impact of Adoption of Topic 606 and Topic 842 on the Condensed Consolidated Balance Sheet) (Details) - USD ($)
$ in Thousands
Dec. 28, 2018
Dec. 30, 2017
Dec. 29, 2017
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]      
Contract assets: unbilled collaboration revenue, gross: Current portion $ 0 $ 9,588  
Contract assets: unbilled collaboration revenue, gross: Long-term portion 0 12,247  
Other receivables 162,771 11,635 $ 77,300
Property and equipment, net 50,897 11,213 25,743
Operating lease right-of-use assets 5,867 8,579 0
Current portion of deferred revenue 0 8,393 31,984
Long-term portion of deferred revenue 15,897 25,441 238,520
Other current liabilities 21,825 19,323 16,150
Long-term portion of lease liabilities 14,965 13,323  
Accumulated deficit $ (880,363) (1,570,433) (1,829,172)
Calculated under Revenue Guidance in Effect before Topic 606 [Member]      
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]      
Contract assets: unbilled collaboration revenue, gross: Current portion     0
Contract assets: unbilled collaboration revenue, gross: Long-term portion     0
Other receivables     3,892
Property and equipment, net     25,743
Operating lease right-of-use assets     0
Current portion of deferred revenue     31,984
Long-term portion of deferred revenue     238,520
Other current liabilities     16,150
Long-term portion of lease liabilities     14,938
Accumulated deficit     $ (1,829,172)
ASU 2014-09 | Adjustments Due to the Adoption of Topic 606      
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]      
Contract assets: unbilled collaboration revenue, gross: Current portion   9,588  
Contract assets: unbilled collaboration revenue, gross: Long-term portion   12,247  
Current portion of deferred revenue   (23,591)  
Long-term portion of deferred revenue   (213,079)  
Accumulated deficit   258,505  
Restatement | ASU 2016-02      
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]      
Other receivables   7,743  
Property and equipment, net   (14,530)  
Operating lease right-of-use assets   8,579  
Other current liabilities   3,173  
Long-term portion of lease liabilities   (1,615)  
Accumulated deficit   $ 234