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Collaboration Agreements (Other Collaborations, Narrative) (Details)
1 Months Ended 12 Months Ended
Nov. 30, 2015
Dec. 28, 2018
USD ($)
clinical_trial
Collaborative Arrangement with Genentech    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Percentage of share of the Company in promotions 25.00%  
Number of clinical trials (more than) | clinical_trial   50
Collaborative Arrangement with Daiichi Sankyo    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Maximum amount eligible for development and regulatory milestones   $ 110,000,000
Collaborative Arrangement with Daiichi Sankyo | Maximum    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Percent of royalty on net sales   0.50%
Collaborative Arrangement with BMS    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Maximum amount eligible for development and regulatory milestones   $ 240,000,000
Maximum amount eligible for royalties on sales under collaborations agreement   $ 150,000,000
Profit Sharing Tier One | Collaborative Arrangement with Genentech    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Percent of profits   50.00%
Profit Sharing Tier Two | Collaborative Arrangement with Genentech | Minimum    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Profit threshold   $ 200,000,000
Profit Sharing Tier Three | Collaborative Arrangement with Genentech    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Percent of profits   30.00%
Profit Sharing Tier Three | Collaborative Arrangement with Genentech | Maximum    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Profit threshold   $ 400,000,000