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v3.19.1

Subsequent Event (Details) |  |  | 12 Months Ended |
--- | --- | --- | --- | ---
Apr. 29, 2019 USD ($) | Apr. 15, 2019 USD ($) ft² | Dec. 28, 2018 USD ($) | Apr. 01, 2019 USD ($) ft²
Collaborative Arrangement with Takeda |  |  |  |
Subsequent Event [Line Items] |  |  |  |
Milestone payments earned |  |  | $ 10,000,000 |
Subsequent Event | Collaborative Arrangement with Takeda |  |  |  |
Subsequent Event [Line Items] |  |  |  |
Limit on reimbursement per year | $ 1,000,000 |  |  |
Increase in maximum amount eligible for development and regulatory milestones | 12,000,000 |  |  |
Maximum amount eligible for development and regulatory milestones | 102,000,000 |  |  |
Milestone payments earned | 16,000,000 |  |  |
Increase in maximum amount eligible for commercial milestones under collaborations agreement | 3,000,000 |  |  |
Maximum amount eligible for commercial milestones under collaborations agreement | $ 86,000,000 |  |  |
Subsequent Event | Corporate Headquarters, Alameda, California |  |  |  |
Subsequent Event [Line Items] |  |  |  |
Operating lease, expansion (in square feet) | ft² |  |  |  | 37,544
Operating lease, surrendered (in square feet) | ft² |  |  |  | 2,703
Tenant improvement allowance |  |  |  | $ 1,700,000
Area of lease property (in square feet) | ft² |  | 169,606 |  |
Aggregate contractual base rent |  | $ 34,600,000 |  |
Subsequent Event | Corporate Headquarters, Alameda, California | Minimum |  |  |  |
Subsequent Event [Line Items] |  |  |  |
Monthly base rent |  | 224,505 |  |
Operating lease, not yet commenced, monthly base rent |  | 71,334 |  |
Subsequent Event | Corporate Headquarters, Alameda, California | Maximum |  |  |  |
Subsequent Event [Line Items] |  |  |  |
Monthly base rent |  | 283,933 |  |
Operating lease, not yet commenced, monthly base rent |  | $ 90,481 |  |

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