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Collaboration Agreements (Tables)
3 Months Ended
Mar. 29, 2019
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of Collaborative Revenues Under Collaboration Agreement
Profits on U.S. commercialization and Royalty revenues on ex-U.S. sales were as follows (in thousands):
 
Three Months Ended March 31,
 
2019
 
2018
Profits on U.S. commercialization
$
1,055

 
$
1,373

Royalty revenues on ex-U.S. sales
$
1,490

 
$
1,349

Collaboration revenues under the collaboration agreement with Ipsen were as follows (in thousands):
 
Three Months Ended March 31,
 
2019
 
2018
Ipsen collaboration revenues
$
21,868

 
$
53,809

Collaboration revenues under the collaboration agreement with Takeda were as follows (in thousands):
 
Three Months Ended March 31,
 
2019
 
2018
Takeda collaboration revenues
$
11,493

 
$
2,917