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Condensed Consolidated Statements of Income - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 28, 2019
Jun. 29, 2018
Jun. 28, 2019
Jun. 29, 2018
Total revenues $ 240,275 $ 186,108 $ 455,762 $ 399,827
Operating expenses:        
Cost of goods sold 7,539 5,997 15,040 11,636
Research and development 81,932 42,488 145,221 80,245
Selling, general and administrative 58,815 51,853 118,953 105,869
Total operating expenses 148,286 100,338 279,214 197,750
Income from operations 91,989 85,770 176,548 202,077
Other income (expense), net:        
Interest income 6,975 2,697 13,062 4,592
Other, net 803 (72) 828 97
Total other income (expense), net: 7,778 2,625 13,890 4,689
Income before income taxes 99,767 88,395 190,438 206,766
Provision for income taxes (20,725) (901) (35,621) (3,415)
Net income $ 79,042 $ 87,494 $ 154,817 $ 203,351
Net income per share, basic (in dollars per share) $ 0.26 $ 0.29 $ 0.51 $ 0.68
Net income per share, diluted (in dollars per share) $ 0.25 $ 0.28 $ 0.49 $ 0.65
Shares used in computing net income per share, basic (in shares) 302,188 297,336 301,365 296,874
Shares used in computing net income per share, diluted (in shares) 314,911 312,241 314,786 313,024
Net product revenues        
Total revenues $ 193,675 $ 145,836 $ 373,256 $ 280,108
Collaboration revenue        
Total revenues $ 46,600 $ 40,272 $ 82,506 $ 119,719