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Collaboration Agreements - Daiichi Sankyo (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Jun. 30, 2019
Sep. 27, 2019
Sep. 28, 2018
Sep. 27, 2019
Sep. 28, 2018
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Total revenues   $ 271,703 $ 225,397 $ 727,465 $ 625,224
Collaboration revenue          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Total revenues   79,935 62,451 162,441 182,170
Collaboration Agreement with Daiichi Sankyo          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Total revenues   $ 0 $ 0 $ 20,130 $ 20,000
Percent of royalty on net sale       0.50%  
Collaboration Agreement with Daiichi Sankyo | Collaboration revenue          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Total revenues $ 20,000