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Revenues (Tables)
12 Months Ended
Jan. 03, 2020
Revenue from Contract with Customer [Abstract]  
Disaggregation of Revenue
Revenues consisted of the following (in thousands):
 
Year Ended December 31,
 
2019
 
2018
 
2017
Product revenues:
 
 
 
 
 
Gross product revenues
$
957,621

 
$
738,529

 
$
402,569

Discounts and allowances
(197,671
)
 
(119,250
)
 
(53,561
)
Net product revenues
759,950

 
619,279

 
349,008

Collaboration revenues:
 
 
 
 
 
License revenues
161,299

 
192,188

 
96,637

Research and development service revenues
49,965

 
39,501

 
8,737

Other collaboration revenues
(3,439
)
 
2,858

 
(1,905
)
Total collaboration revenues
207,825

 
234,547

 
103,469

Total revenues
$
967,775

 
$
853,826

 
$
452,477


Net product revenues disaggregated by product were as follows (in thousands):
 
Year Ended December 31,
 
2019
 
2018
 
2017
CABOMETYX
$
733,421

 
$
599,946

 
$
324,000

COMETRIQ
26,529

 
19,333

 
25,008

Net product revenues
$
759,950

 
$
619,279

 
$
349,008


Revenues Disaggregated by Significant Customer
The percentage of total revenues by customer who individually accounted for 10% or more of our total revenues were as follows:
 
Year Ended December 31,
 
2019
 
2018
 
2017
Ipsen
16
%
 
21
%
 
15
%
Affiliates of CVS Health Corporation
15
%
 
13
%
 
16
%
Affiliates of McKesson Corporation
12
%
 
12
%
 
11
%
Affiliates of AmerisourceBergen Corporation
10
%
 
8
%
 
8
%
Accredo Health, Incorporated
9
%
 
9
%
 
11
%
Diplomat Specialty Pharmacy
5
%
 
9
%
 
18
%

Revenues Disaggregated by Geographic Region
Revenues by geographic region were as follows (in thousands):
 
Year Ended December 31,
 
2019
 
2018
 
2017
U.S.
$
770,244

 
$
632,927

 
$
367,906

Europe
152,771

 
182,879

 
69,792

Japan
44,760

 
38,020

 
14,779

Total revenues
$
967,775

 
$
853,826

 
$
452,477


Activities and Ending Reserve Balances for Significant Categories of Discounts and Allowances
The activities and ending reserve balances for each significant category of discounts and allowances (which constitute variable consideration) were as follows (in thousands):
 
Chargebacks and Discounts for Prompt Payment
 
Other Customer Credits/Fees and Co-pay Assistance
 
Rebates
 
Total
Balance at December 31, 2017
$
1,928

 
$
1,795

 
$
5,770

 
$
9,493

Provision related to sales made in:
 
 
 
 
 
 
 
Current period
75,543

 
13,017

 
31,040

 
119,600

Prior periods
(403
)
 
206

 
(153
)
 
(350
)
Payments and customer credits issued
(74,746
)
 
(11,980
)
 
(24,741
)
 
(111,467
)
Balance at December 31, 2018
2,322

 
3,038

 
11,916

 
17,276

Provision related to sales made in:
 
 
 
 
 
 
 
Current period
129,936

 
15,605

 
48,250

 
193,791

Prior periods
3,989

 
(111
)
 
2

 
3,880

Payments and customer credits issued
(128,733
)
 
(15,035
)
 
(44,946
)
 
(188,714
)
Balance at December 31, 2019
$
7,514

 
$
3,497

 
$
15,222

 
$
26,233