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Collaboration Agreements - Royalty Revenues under the Collaboration Agreement with Genentech (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jul. 03, 2020
Jun. 28, 2019
Jul. 03, 2020
Jun. 28, 2019
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Royalty revenues on ex-U.S. sales $ 259,479 $ 240,275 $ 486,394 $ 455,762
Cotellic | Collaborative Arrangement with Genentech        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Profits on U.S. commercialization 1,376 1,349 2,783 2,404
Royalty revenues on ex-U.S. sales $ 1,125 $ 1,323 $ 2,434 $ 2,813