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Collaboration Agreements (StemSynergy Collaboration, Narrative) (Details) - Collaborative Arrangement With StemSynergy - USD ($) $ in Millions | 12 Months Ended |
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Dec. 28, 2018 | Jan. 01, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Upfront and milestone payments | $ 3.0 |
First Product To Reach Market |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Eligible payment from collaboration for development and regulatory milestone achievement under collaborations agreement |  | $ 56.5

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- Definition Eligible Payment From Collaboration For Development And Regulatory Milestone Achievement Under Collaborations Agreement + References No definition available. + Details
Name: | exel_EligiblePaymentFromCollaborationForDevelopmentAndRegulatoryMilestoneAchievementUnderCollaborationsAgreement
Namespace Prefix: | exel_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition Upfront and milestone payments. + References No definition available. + Details
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Namespace Prefix: | exel_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

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- Details
Name: | us-gaap_TypeOfArrangementAxis=exel_CollaborativeArrangementWithStemSynergyMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | exel_MilestoneObjectiveAxis=exel_FirstProductToReachMarketMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |