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Collaboration Agreements (Tables)
12 Months Ended
Jan. 01, 2021
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of Collaborative Revenues Under Collaboration Agreement
Revenues under the collaboration agreement with Ipsen were as follows (in thousands):
 Year Ended December 31,
 202020192018
License revenues$93,495 $117,360 $157,569 
Collaboration services revenues58,136 35,411 25,310 
Total$151,631 $152,771 $182,879 
Collaboration services revenues under the collaboration agreement with Takeda were as follows (in thousands):
 Year Ended December 31,
 202020192018
License revenues$61,115 $18,112 $9,055 
Collaboration services revenues20,557 6,510 8,965 
Total collaboration revenues$81,672 $24,622 $18,020 
Profits and losses on the U.S. commercialization and royalty revenues on ex-U.S. sales under the collaboration agreement with Genentech were as follows (in thousands):
 Year Ended December 31,
 202020192018
Profits on U.S. commercialization$6,261 $4,615 $8,084 
Royalty revenues on ex-U.S. sales$5,079 $5,679 $5,564