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Consolidated Statements of Income - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Jan. 01, 2021
Jan. 03, 2020
Dec. 28, 2018
Revenues:      
Total revenues $ 987,538 $ 967,775 $ 853,826
Operating expenses:      
Cost of goods sold 36,272 33,097 26,348
Research and development 547,851 336,964 182,257
Selling, general and administrative 293,355 228,244 206,366
Total operating expenses 877,478 598,305 414,971
Income from operations 110,060 369,470 438,855
Interest income 19,865 27,959 12,840
Other income, net 912 680 397
Income before income taxes 130,837 398,109 452,092
Provision for (benefit from) income taxes 19,056 77,097 (237,978)
Net income $ 111,781 $ 321,012 $ 690,070
Net income per share:      
Basic (in dollars per share) $ 0.36 $ 1.06 $ 2.32
Diluted (in dollars per share) $ 0.35 $ 1.02 $ 2.21
Weighted-average common shares outstanding:      
Basic (in shares) 308,271 302,584 297,892
Diluted (in shares) 318,001 315,009 312,803
Net product revenues      
Revenues:      
Total revenues $ 741,550 $ 759,950 $ 619,279
License revenues      
Revenues:      
Total revenues 167,295 165,914 200,272
Collaboration services revenues      
Revenues:      
Total revenues $ 78,693 $ 41,911 $ 34,275