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Collaboration Agreements (Takeda Collaboration, Narrative) (Details) - USD ($) $ in Millions	3 Months Ended								12 Months Ended
	Jan. 01, 2021	Oct. 02, 2020	Jul. 03, 2020	Apr. 03, 2020	Jan. 03, 2020	Sep. 27, 2019	Jun. 28, 2019	Mar. 29, 2019	Jan. 01, 2021	Jan. 03, 2020	Dec. 28, 2018	Dec. 31, 2017
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payments earned to date	$ 350.0								$ 350.0
Milestone payments earned	29.4	$ 13.5	$ 43.5	$ 0.1	$ 15.1	$ 50.6	$ 20.4	$ 10.0
Remaining performance obligation	86.1								$ 86.1
Collaborative Arrangement with GlaxoSmithKline
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration agreement percent of royalty on net sale									3.00%
Collaborative arrangement with Takeda
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sales volume period									6 years
Upfront payments												$ 50.0
Milestone payments earned to date	92.0								$ 92.0
Milestone payments earned									66.0	$ 16.0	$ 10.0
Milestone payments, yet to be earned	15.0								15.0
Maximum amount eligible for commercial milestones under collaborations agreement	139.0								139.0
Remaining performance obligation	$ 44.8								44.8
Collaborative arrangement with Takeda | Initial
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Royalty tier									$ 300.0
Collaborative arrangement with Takeda | Initial | Minimum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percent of royalty on net sale									15.00%
Collaborative arrangement with Takeda | Initial | Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percent of royalty on net sale									24.00%
Collaborative arrangement with Takeda | Final tier | Minimum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percent of royalty on net sale									20.00%
Collaborative arrangement with Takeda | Final tier | Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percent of royalty on net sale									30.00%
Collaborative arrangement with Takeda | Japan
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development arrangement performed for others, reimbursement for costs incurred, percent									100.00%
Collaboration period to achieve specified levels of commercial performance									2 years

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 13
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=121604090&loc=SL49130556-203045

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