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Collaboration Agreements, In-Licensing Arrangements And Business Development Activities - Royalty Revenues under the Collaboration Agreement with Genentech (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jul. 02, 2021	Jul. 03, 2020	Jul. 02, 2021	Jul. 03, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Royalty revenues on ex-U.S. sales	$ 385,177	$ 259,479	$ 655,407	$ 486,394
Collaborative Arrangement with Genentech | Cotellic
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Profits on U.S. commercialization	2,160	1,376	3,954	2,783
Royalty revenues on ex-U.S. sales	$ 782	$ 1,125	$ 1,733	$ 2,434

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