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Collaboration Agreements, In-Licensing Arrangements And Business Development Activities - Collaboration Revenues under the Collaboration Agreement with Takeda (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Oct. 01, 2021
Oct. 02, 2020
Oct. 01, 2021
Oct. 02, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues $ 328,423 $ 231,092 $ 983,830 $ 717,486
Collaborative Arrangement with Takeda        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues 22,734 22,984 34,291 49,194
License revenues        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues 49,694 33,205 116,862 113,318
License revenues | Collaborative Arrangement with Takeda        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues 20,078 9,780 23,476 32,726
Collaboration services revenues        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues 15,612 29,300 92,391 62,971
Collaboration services revenues | Collaborative Arrangement with Takeda        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues $ 2,656 $ 13,204 $ 10,815 $ 16,468