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Collaboration Agreements, In-Licensing Arrangements And Business Development Activities - Royalty Revenues under the Collaboration Agreement with Genentech (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Oct. 01, 2021	Oct. 02, 2020	Oct. 01, 2021	Oct. 02, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Royalty revenues on ex-U.S. sales	$ 328,423	$ 231,092	$ 983,830	$ 717,486
Collaborative Arrangement with Genentech | Cotellic
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Profits on U.S. commercialization	1,743	1,595	5,697	4,378
Royalty revenues on ex-U.S. sales	$ 1,576	$ 1,370	$ 3,309	$ 3,804

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