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Condensed Consolidated Statements of Income (Loss) - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 9 Months Ended
Oct. 01, 2021
Oct. 02, 2020
Oct. 01, 2021
Oct. 02, 2020
Revenues:        
Total revenues $ 328,423 $ 231,092 $ 983,830 $ 717,486
Operating expenses:        
Cost of goods sold 11,874 8,725 39,956 27,235
Research and development 163,370 176,762 471,448 393,572
Selling, general and administrative 101,558 88,185 302,404 210,916
Total operating expenses 276,802 273,672 813,808 631,723
Income (loss) from operations 51,621 (42,580) 170,022 85,763
Interest income 1,658 3,994 6,231 16,376
Other income (expense), net (19) 565 (120) 571
Income (loss) before income taxes 53,260 (38,021) 176,133 102,710
Provision for (benefit from) income taxes 15,056 (5,981) 40,236 19,317
Net income (loss) $ 38,204 $ (32,040) $ 135,897 $ 83,393
Net income (loss) per share:        
Basic (in dollars per share) $ 0.12 $ (0.10) $ 0.43 $ 0.27
Diluted (in dollars per share) $ 0.12 $ (0.10) $ 0.42 $ 0.26
Weighted-average common shares outstanding:        
Basic (in shares) 315,380 309,116 313,990 307,437
Diluted (in shares) 322,022 309,116 322,084 317,495
Net product revenues        
Revenues:        
Total revenues $ 263,117 $ 168,587 $ 774,577 $ 541,197
License revenues        
Revenues:        
Total revenues 49,694 33,205 116,862 113,318
Collaboration services revenues        
Revenues:        
Total revenues $ 15,612 $ 29,300 $ 92,391 $ 62,971