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Collaboration Agreements And Business Development Activities - Collaboration Revenues under the Collaboration Agreement with Ipsen (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2021 | Jan. 01, 2021 | Jan. 03, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | $ 1,434,970 | $ 987,538 | $ 967,775
Collaborative Arrangement with Ipsen |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | 302,073 | 151,631 | 152,771
License revenues |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | 249,956 | 167,295 | 165,914
License revenues | Collaborative Arrangement with Ipsen |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | 207,982 | 93,495 | 117,360
Collaboration services revenues |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | 107,758 | 78,693 | 41,911
Collaboration services revenues | Collaborative Arrangement with Ipsen |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | $ 94,091 | $ 58,136 | $ 35,411

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