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Revenues (Tables)
 3 Months Ended
Apr. 01, 2022
Revenue from Contract with Customer [Abstract]  
Schedule of Disaggregation of Revenue
Revenues consisted of the following (in thousands):
Three Months Ended March 31,
20222021
Product revenues:
Gross product revenues$448,237 $314,205 
Discounts and allowances(137,939)(86,993)
Net product revenues310,298 227,212 
Collaboration revenues:
License revenues32,067 27,528 
Collaboration services revenues13,615 15,490 
Total collaboration revenues45,682 43,018 
Total revenues$355,980 $270,230 
Net product revenues by product were as follows (in thousands):
Three Months Ended March 31,
20222021
CABOMETYX$302,812 $223,595 
COMETRIQ7,486 3,617 
Net product revenues$310,298 $227,212 
Schedule of Concentration Risks
The percentage of total revenues by customer who individually accounted for 10% or more of our total revenues were as follows:
Three Months Ended March 31,
20222021
Affiliates of McKesson Corporation19 %13 %
Affiliates of CVS Health Corporation17 %15 %
Affiliates of AmerisourceBergen Corporation17 %14 %
Ipsen Pharma SAS10 %13 %
Affiliates of Optum Specialty Pharmacy10 %9 %
The percentage of trade receivables by customer who individually accounted for 10% or more of our trade receivables were as follows:
March 31, 2022December 31, 2021
Affiliates of McKesson Corporation22 %10 %
Ipsen Pharma SAS21 %50 %
Affiliates of AmerisourceBergen Corporation21 %11 %
Affiliates of CVS Health Corporation15 %9 %
Schedule of Revenues Disaggregated by Geographic Region
Revenues by geographic region were as follows (in thousands):
Three Months Ended March 31,
20222021
U.S.$314,065 $229,957 
Europe34,527 33,806 
Japan7,388 6,467 
Total revenues$355,980 $270,230 
Schedule of Activities and Ending Reserve Balances for Significant Categories of Discounts and Allowances
The activities and ending reserve balances for each significant category of discounts and allowances, which constitute variable consideration, were as follows (in thousands):
Chargebacks, Discounts for Prompt Payment and Other
Other Customer Credits/Fees and Co-pay Assistance
Rebates
Total
Balance at December 31, 2021
$14,625 $8,875 $24,825 $48,325 
Provision related to sales made in:
Current period86,620 12,087 38,734 137,441 
Prior periods154 (43)387 498 
Payments and customer credits issued(83,004)(10,227)(24,641)(117,872)
Balance at March 31, 2022
$18,395 $10,692 $39,305 $68,392 
Schedule of Other Assets and Other Liabilities Contract assets and liabilities were as follows (in thousands):
March 31, 2022December 31, 2021
Contract assets (1)
$3,235 $1,665 
Contract liabilities:
Current portion (2)
$7,349 $7,814 
Long-term portion (3)
8,035 8,739 
Total contract liabilities$15,384 $16,553 
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(1)    Presented in other long-term assets in the accompanying Condensed Consolidated Balance Sheets.
(2)    Presented in other current liabilities in the accompanying Condensed Consolidated Balance Sheets.
(3)    Presented in the long-term portion of deferred revenues in the accompanying Condensed Consolidated Balance Sheets