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Collaboration Agreements And Business Development Activities - Collaboration Revenues under the Collaboration Agreement with Takeda (Details) - USD ($)
$ in Thousands
 3 Months Ended
Apr. 01, 2022
Apr. 02, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues $ 355,980 $ 270,230
Collaborative Arrangement with Takeda    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues 6,067 5,436
License revenues    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues 32,067 27,528
License revenues | Collaborative Arrangement with Takeda    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues 2,365 1,301
Collaboration services revenues    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues 13,615 15,490
Collaboration services revenues | Collaborative Arrangement with Takeda    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues $ 3,702 $ 4,135