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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 6 Months Ended
Jul. 01, 2022
Jul. 02, 2021
Statement of Cash Flows [Abstract]    
Net income $ 139,245 $ 97,693
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation and amortization 9,266 6,895
Stock-based compensation 44,381 62,688
Non-cash lease expense 6,443 2,586
Deferred taxes 0 22,800
Other, net 4,359 22,831
Changes in operating assets and liabilities:    
Trade receivables, net 46,693 (12,313)
Inventory (8,322) (8,020)
Prepaid expenses and other assets (26,025) (12,296)
Deferred revenue (1,831) 9,346
Accrued collaboration liabilities (53,263) 2,972
Accounts payable and other liabilities 17,903 25,863
Net cash provided by operating activities 178,849 221,045
Cash flows from investing activities:    
Purchases of property, equipment and other (17,946) (33,768)
Purchases of investments (692,091) (688,903)
Proceeds from maturities and sales of investments 500,356 714,081
Net cash used in investing activities (209,681) (8,590)
Cash flows from financing activities:    
Proceeds from issuance of common stock under equity incentive plans 15,791 15,487
Taxes paid related to net share settlement of equity awards (11,164) (9,413)
Net cash provided by financing activities 4,627 6,074
Net (decrease) increase in cash, cash equivalents, and restricted cash equivalents (26,205) 218,529
Cash, cash equivalents and restricted cash equivalents at beginning of period 663,891 320,772
Cash, cash equivalents and restricted cash equivalents at end of period 637,686 539,301
Non-cash operating activities:    
Right-of-use assets obtained in exchange for lease obligations 120,363 4,893
Non-cash investing activities:    
Unpaid liabilities incurred for purchases of property and equipment 3,570 5,125
Unpaid liabilities incurred in asset acquisition 500 9,000
Unpaid liabilities incurred for unsettled investment purchases $ 0 $ 7,378