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Revenues - Activities and Ending Reserve Balances for Significant Categories of Discounts and Allowances (Details)
$ in Thousands
 9 Months Ended
Sep. 30, 2022
USD ($)
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]  
Balance at December 31, 2021 $ 48,325
Provision related to sales made in:  
Current period 403,270
Prior periods 357
Payments and customer credits issued (386,763)
Balance at September 30, 2022 65,189
Chargebacks, Discounts for Prompt Payment and Other  
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]  
Balance at December 31, 2021 14,625
Provision related to sales made in:  
Current period 261,143
Prior periods 632
Payments and customer credits issued (255,002)
Balance at September 30, 2022 21,398
Other Customer Credits/Fees and Co-pay Assistance  
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]  
Balance at December 31, 2021 8,875
Provision related to sales made in:  
Current period 36,847
Prior periods (169)
Payments and customer credits issued (32,765)
Balance at September 30, 2022 12,788
Rebates  
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]  
Balance at December 31, 2021 24,825
Provision related to sales made in:  
Current period 105,280
Prior periods (106)
Payments and customer credits issued (98,996)
Balance at September 30, 2022 $ 31,003