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Condensed Consolidated Statements of Income - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2022
Oct. 01, 2021
Sep. 30, 2022
Oct. 01, 2021
Revenues:        
Total revenues $ 411,738 $ 328,423 $ 1,187,145 $ 983,830
Operating expenses:        
Cost of goods sold 15,305 11,874 41,989 39,956
Research and development 198,837 163,370 554,989 471,448
Selling, general and administrative 114,983 101,558 340,605 302,404
Total operating expenses 329,125 276,802 937,583 813,808
Income from operations 82,613 51,621 249,562 170,022
Interest income 9,498 1,658 16,077 6,231
Other income (expense), net (69) (19) 140 (120)
Income before income taxes 92,042 53,260 265,779 176,133
Provision for income taxes 18,832 15,056 53,324 40,236
Net income $ 73,210 $ 38,204 $ 212,455 $ 135,897
Net income per share:        
Basic (in dollars per share) $ 0.23 $ 0.12 $ 0.66 $ 0.43
Diluted (in dollars per share) $ 0.23 $ 0.12 $ 0.65 $ 0.42
Weighted-average common shares outstanding:        
Basic (in shares) 322,148 315,380 320,949 313,990
Diluted (in shares) 325,066 322,022 324,420 322,084
Net product revenues        
Revenues:        
Total revenues $ 366,482 $ 263,117 $ 1,023,824 $ 774,577
License revenues        
Revenues:        
Total revenues 34,384 49,694 123,977 116,862
Collaboration services revenues        
Revenues:        
Total revenues $ 10,872 $ 15,612 $ 39,344 $ 92,391