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Collaboration Agreements And Business Development Activities - Collaboration Revenues under the Collaboration Agreement with Takeda (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 30, 2022 | Dec. 31, 2021 | Jan. 01, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | $ 1,611,062 | $ 1,434,970 | $ 987,538
Collaborative arrangement with Takeda |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | 24,238 | 39,725 | 81,672
License revenues |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | 162,056 | 249,956 | 167,295
License revenues | Collaborative arrangement with Takeda |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | 11,335 | 26,058 | 61,115
Collaboration services revenues |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | 47,763 | 107,758 | 78,693
Collaboration services revenues | Collaborative arrangement with Takeda |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Total revenues | $ 12,903 | $ 13,667 | $ 20,557

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