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Collaboration Agreements And Business Development Activities - Collaboration Revenues under the Collaboration Agreement with Takeda (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 30, 2022
Dec. 31, 2021
Jan. 01, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total revenues $ 1,611,062 $ 1,434,970 $ 987,538
Collaborative arrangement with Takeda      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total revenues 24,238 39,725 81,672
License revenues      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total revenues 162,056 249,956 167,295
License revenues | Collaborative arrangement with Takeda      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total revenues 11,335 26,058 61,115
Collaboration services revenues      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total revenues 47,763 107,758 78,693
Collaboration services revenues | Collaborative arrangement with Takeda      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total revenues $ 12,903 $ 13,667 $ 20,557