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Consolidated Statements of Income - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 30, 2022
Dec. 31, 2021
Jan. 01, 2021
Revenues:      
Total revenues $ 1,611,062 $ 1,434,970 $ 987,538
Operating expenses:      
Cost of goods sold 57,909 52,873 36,272
Research and development 891,813 693,716 547,851
Selling, general and administrative 459,856 401,715 293,355
Total operating expenses 1,409,578 1,148,304 877,478
Income from operations 201,484 286,666 110,060
Interest income 33,065 7,672 19,865
Other income (expense), net (197) (184) 912
Income before income taxes 234,352 294,154 130,837
Provision for income taxes 52,070 63,091 19,056
Net income $ 182,282 $ 231,063 $ 111,781
Net income per share:      
Basic (in dollars per share) $ 0.57 $ 0.73 $ 0.36
Diluted (in dollars per share) $ 0.56 $ 0.72 $ 0.35
Weighted-average common shares outstanding:      
Basic (in shares) 321,526 314,884 308,271
Diluted (in shares) 324,556 322,359 318,001
Net product revenues      
Revenues:      
Total revenues $ 1,401,243 $ 1,077,256 $ 741,550
License revenues      
Revenues:      
Total revenues 162,056 249,956 167,295
Collaboration services revenues      
Revenues:      
Total revenues $ 47,763 $ 107,758 $ 78,693