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Revenues - Activities and Ending Reserve Balances for Significant Categories of Discounts and Allowances (Details)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
USD ($)
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]  
Balance at December 31, 2022 $ 77,231
Provision related to sales made in:  
Current period 158,985
Prior periods (1,063)
Payments and customer credits issued (147,598)
Balance at March 31, 2023 87,555
Chargebacks, Discounts for Prompt Payment and Other  
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]  
Balance at December 31, 2022 26,881
Provision related to sales made in:  
Current period 94,959
Prior periods 141
Payments and customer credits issued (100,831)
Balance at March 31, 2023 21,150
Other Customer Credits/Fees and Co-pay Assistance  
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]  
Balance at December 31, 2022 14,924
Provision related to sales made in:  
Current period 14,913
Prior periods (1,117)
Payments and customer credits issued (13,637)
Balance at March 31, 2023 15,083
Rebates  
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]  
Balance at December 31, 2022 35,426
Provision related to sales made in:  
Current period 49,113
Prior periods (87)
Payments and customer credits issued (33,130)
Balance at March 31, 2023 $ 51,322