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Collaboration Agreements And Business Development Activities - Collaboration Revenues under the Collaboration Agreement with Takeda (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
Apr. 01, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues $ 408,788 $ 355,980
Collaborative Arrangement with Takeda    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues 6,223 6,067
License revenues    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues 38,292 32,067
License revenues | Collaborative Arrangement with Takeda    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues 2,849 2,365
Collaboration services revenues    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues 7,096 13,615
Collaboration services revenues | Collaborative Arrangement with Takeda    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Total revenues $ 3,374 $ 3,702