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Revenues - Net Product Revenues Disaggregated by Product (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2023
Jul. 01, 2022
Jun. 30, 2023
Jul. 01, 2022
Disaggregation of Revenue [Line Items]        
Total revenues $ 469,848 $ 419,427 $ 878,636 $ 775,407
Net product revenues        
Disaggregation of Revenue [Line Items]        
Total revenues 409,646 347,044 773,046 657,342
CABOMETYX        
Disaggregation of Revenue [Line Items]        
Total revenues 403,292 339,159 765,065 641,971
COMETRIQ        
Disaggregation of Revenue [Line Items]        
Total revenues $ 6,354 $ 7,885 $ 7,981 $ 15,371