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Collaboration Agreements And Business Development Activities - Collaboration Revenues under the Collaboration Agreement with Takeda (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2023
Jul. 01, 2022
Jun. 30, 2023
Jul. 01, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues $ 469,848 $ 419,427 $ 878,636 $ 775,407
Collaborative Arrangement with Takeda        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues 16,104 6,485 22,327 12,552
License revenues        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues 52,747 57,526 91,039 89,593
License revenues | Collaborative Arrangement with Takeda        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues 11,362 2,700 14,211 5,065
Collaboration services revenues        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues 7,455 14,857 14,551 28,472
Collaboration services revenues | Collaborative Arrangement with Takeda        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Total revenues $ 4,742 $ 3,785 $ 8,116 $ 7,487