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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2023
Jul. 01, 2022
Statement of Cash Flows [Abstract]    
Net income $ 121,206 $ 139,245
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation 12,895 9,266
Stock-based compensation 41,561 44,381
Non-cash lease expense 13,980 6,443
Acquired in-process research and development technology 37,500 1,500
Other, net (8,176) 2,859
Changes in operating assets and liabilities:    
Trade receivables, net (18,317) 46,693
Inventory (12,815) (8,322)
Prepaid expenses and other assets 8,548 (26,025)
Deferred revenue (545) (1,831)
Accrued collaboration liabilities 3,272 (53,263)
Accounts payable and other liabilities 6,277 17,903
Net cash provided by operating activities 205,386 178,849
Cash flows from investing activities:    
Purchases of property, equipment and other (17,961) (12,946)
Acquired in-process research and development technology (38,000) (5,000)
Purchases of investments (641,328) (692,091)
Proceeds from maturities and sales of investments 573,912 500,356
Net cash used in investing activities (123,377) (209,681)
Cash flows from financing activities:    
Payments for repurchases of common stock (124,239) 0
Proceeds from issuance of common stock under equity incentive and stock purchase plans 17,422 15,791
Taxes paid related to net share settlement of equity awards (13,389) (11,164)
Net cash provided by (used in) financing activities (120,206) 4,627
Net decrease in cash and cash equivalents (38,197) (26,205)
Cash and cash equivalents at beginning of period 502,677 663,891
Cash and cash equivalents at end of period 464,480 637,686
Non-cash operating activities:    
Right-of-use assets obtained in exchange for lease obligations $ 13,584 $ 120,363